01. Beta-Blocker drug is following?
A. Atropine
B. Esmolol
C. Acetylcholine
D. Succinylcholine
E. Tamsulosin
Answer: B. Esmolol
02. Which one of the following drugs is an adrenergic antagonist Alpha Blocker drug?
A. Phenoxybenzamine
B. Metoprolol
C. Mecamylamine
D. Atracurium
E. Tacrine
Answer: A. Phenoxybenzamine
03. Which of the following drug belongs to lincosamide antibiotics?
A. Clindamycin
B. Linezolid
C. Ciprofloxacin
D. Oxytetracycline
E. Sulbactam
Answer: A. Clindamycin
A. Atropine
B. Esmolol
C. Acetylcholine
D. Succinylcholine
E. Tamsulosin
Answer: B. Esmolol
02. Which one of the following drugs is an adrenergic antagonist Alpha Blocker drug?
A. Phenoxybenzamine
B. Metoprolol
C. Mecamylamine
D. Atracurium
E. Tacrine
Answer: A. Phenoxybenzamine
03. Which of the following drug belongs to lincosamide antibiotics?
A. Clindamycin
B. Linezolid
C. Ciprofloxacin
D. Oxytetracycline
E. Sulbactam
Answer: A. Clindamycin
04. Which one of the following drugs is a Proteas inhibitor?
A. Abacavir
B. Delavirdine
C. Atazanavir
D. Maraviroc
E. Indanyl carbenicillin
Answer: C. Atazanavir
A. Abacavir
B. Delavirdine
C. Atazanavir
D. Maraviroc
E. Indanyl carbenicillin
Answer: C. Atazanavir
05. Which one of the following drugs is a Proteas inhibitor?
A. Abacavir
B. Delavirdine
C. Darunavir
D. Maraviroc
E. Indanyl carbenicillin
Answer: C. Darunavir
06. Which of the following drug belongs to the Nonnucleoside reverse transcriptase inhibitor?
A. Abacavir
B. Efavirenz
C. Atazanavir
D. Maraviroc
E. Indanyl carbenicillin
Answer: B. Efavirenz
A. Abacavir
B. Delavirdine
C. Darunavir
D. Maraviroc
E. Indanyl carbenicillin
Answer: C. Darunavir
06. Which of the following drug belongs to the Nonnucleoside reverse transcriptase inhibitor?
A. Abacavir
B. Efavirenz
C. Atazanavir
D. Maraviroc
E. Indanyl carbenicillin
Answer: B. Efavirenz
07. Immune-related problem is one of the following?
A. High Blood pressure
B. Fever
C. Aids
D. Headache
A. High Blood pressure
B. Fever
C. Aids
D. Headache
Answer: C. Aids
08. Peripheral resistance is linked with one of the following issues?
A. Blood pressure
B. Fever
C. Aids
D. Headache
Answer: A. Blood pressure
09. Ethacrynic acid belongs to one of the following classes of diuretics?
A. Thiazide Diuretic
B. Loop Diuretics
C. Potassium-sparing diuretics
D. Carbonic anhydrase inhibitors
Answer: B. Loop Diuretics
11. Which of the following drugs causes Rhabdomyolysis as an adverse effect?
A. Digoxin
B. Dronedarone
C. Simvastatin
D. Warfarin
E. Amikacin
Answer: C. Simvastatin
12. Which one of the following drugs is effective only for the influenza A virus?
A. Zanamivir
B. Rimantadine
C. Oseltamivir
D. A & B
E. None of these
Answer: B. Rimantadine
13. 𝛃 receptors have a high sensitivity for which of the following drug?
A. Epinephrine
B. Norepinephrine
C. Isoproterenol
D. A & B
E. All of these
Answer: C. Isoproterenol
14. A cytokine that induces proliferation of antigen-primed T cells along with enhancing the activity of NK cells?
A. Interleukin-1 (IL-1)
B. Interleukin-2 (IL-2)
C. Interferon-gamma
D. Tissue necrosis factor-alpha
Answer: B. Interleukin-2
15. The binding of a drug to plasma proteins will tend to:
A. Decrease half-life.
B. Decrease its rate of glomerular filtration.
C. Increase its rate of biotransformation.
D. Increase its concentration in the plasma.
E. Increase its pharmacological activity
Answer: B. Decrease its rate of glomerular filtration
A. Thiazide Diuretic
B. Loop Diuretics
C. Potassium-sparing diuretics
D. Carbonic anhydrase inhibitors
Answer: B. Loop Diuretics
11. Which of the following drugs causes Rhabdomyolysis as an adverse effect?
A. Digoxin
B. Dronedarone
C. Simvastatin
D. Warfarin
E. Amikacin
Answer: C. Simvastatin
12. Which one of the following drugs is effective only for the influenza A virus?
A. Zanamivir
B. Rimantadine
C. Oseltamivir
D. A & B
E. None of these
Answer: B. Rimantadine
13. 𝛃 receptors have a high sensitivity for which of the following drug?
A. Epinephrine
B. Norepinephrine
C. Isoproterenol
D. A & B
E. All of these
Answer: C. Isoproterenol
14. A cytokine that induces proliferation of antigen-primed T cells along with enhancing the activity of NK cells?
A. Interleukin-1 (IL-1)
B. Interleukin-2 (IL-2)
C. Interferon-gamma
D. Tissue necrosis factor-alpha
Answer: B. Interleukin-2
15. The binding of a drug to plasma proteins will tend to:
A. Decrease half-life.
B. Decrease its rate of glomerular filtration.
C. Increase its rate of biotransformation.
D. Increase its concentration in the plasma.
E. Increase its pharmacological activity
Answer: B. Decrease its rate of glomerular filtration
16. A disease that is characterized by the movement of gastric contents from the stomach into the esophagus?
A. Peptic Ulcer disease
B. GERD
C. Dyspepsia
D. A & B
Answer: B. GERD
A. Peptic Ulcer disease
B. GERD
C. Dyspepsia
D. A & B
Answer: B. GERD
17. Which one of the following drugs has a beta effect (vasodilation) at low doses but when the dose is increased it causes vasoconstriction (Alpha effect) at high doses?
A. Clonidine
B. Metaproterenol
C. Epinephrine
D. Isoproterenol
E. Methoxamine
Answer: C. Epinephrine
A. Clonidine
B. Metaproterenol
C. Epinephrine
D. Isoproterenol
E. Methoxamine
Answer: C. Epinephrine
18. Which of the following drugs has the longest duration of bronchodilation?
A. Epinephrine
B. Isoproterenol
C. Albuterol
D. Salmeterol
E. Metaproterenol
Answer: D. Salmeterol
A. Epinephrine
B. Isoproterenol
C. Albuterol
D. Salmeterol
E. Metaproterenol
Answer: D. Salmeterol
19. One of the OATPs (Organic anion transporting polypeptides) drugs transporters OATP4C1 has a mainly limited distribution to the following?
A. Liver
B. Kidney
C. Skin
D. Heart
E. Stomach
Answer: B. Kidney
20. A patient comes with constipation, incontinence, and a fall in blood pressure. He is being treated for cardiac arrhythmias. Which drug is most likely related to these complaints?
a. Propranolol
b. Verapamil
c. Quinidine
d. Amiodarone
Answer: c. Quinidine
c. Quinidine is the right answer, these are due to extra pharmacology attached with quinidine that is alpha blockade and muscarinic blockade.
A. Liver
B. Kidney
C. Skin
D. Heart
E. Stomach
Answer: B. Kidney
20. A patient comes with constipation, incontinence, and a fall in blood pressure. He is being treated for cardiac arrhythmias. Which drug is most likely related to these complaints?
a. Propranolol
b. Verapamil
c. Quinidine
d. Amiodarone
Answer: c. Quinidine
c. Quinidine is the right answer, these are due to extra pharmacology attached with quinidine that is alpha blockade and muscarinic blockade.
10. Purple toe syndrome is caused by using the therapy of which drug?
A. Digoxin
B. Phenytoin
C. Cyclosporine
D. Warfarin
E. Amikacin
Answer: D. Warfarin
A. Digoxin
B. Phenytoin
C. Cyclosporine
D. Warfarin
E. Amikacin
Answer: D. Warfarin
While treating venous thromboembolism
Unfractionated Heparin anticoagulant effect is monitored either by
A. Partial thromboplastin time (aPPT)
B. Anti-Xa levels
C. Institution specific goal ranges
While Warfarin anticoagulant effect is monitored via
A. International Normalized ratio (INR)
21. A type of hypersensitivity which is a reaction to tissue or membrane antigens(not soluble). Reaction occur when antibodies to surface antigen bind and causes destruction of cell or tissue?
A. Type I
B. Type II
C. Type III
D. Type IV
Answer: Type II hypersensitivity
In type II hypersensitivity antigen is not soluble while in Type III antigen is soluble.
21. Allergic rhinitis or hay fever, food allergies, eczema, asthma and anaphylaxis are following type of hypersensitivity?
A. A. Type I
B. Type II
C. Type III
D. Type IV
Answer: Type I hypersensitivity (mediated by elevated IgE production. IgE bound to on the surface of mast cells and release histamine)
Treatment: forms of atopy are treated by hyposensitization which is repeated injection of controlled doses of allergin or by avoiding allergin.
Asthma treated by inhaled bronchodilators and corticosteroids to ease inflammation on passage
Anaphylactic reactions: Epinephrine as a bronchodilator in emergency, diphenhydramine effective antihistamine and steroid dexamethasone anti inflammatory.
22. Transfusion related reactions caused by incompatible blood type(either the blood typing antigen A, B, or O or the Rh+ or Rh- rhesus antigen) is example of?
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity
D. Type IV hypersensitivity
Answer: Type II hypersensitivity reactions also called cytotoxic or antibody dependent hypersensitivity.
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