PHARMACOLOGY QUIZZES 58 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is used to treat asthma?
A. Hydrochlorothiazide  
B. Repaglinide  
C. Ipratropium
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: C. Ipratropium

02. Which of the following drug belongs to H2 histamine receptor blocker?
A. Niacin
B. Cefoxitin 
C. Glimepiride  
D. Cimetidine 
E. Oxacillin

Answer: D. Cimetidine 


03. A drug that belongs to proton pump inhibitor  is one of the following?
A. Rosiglitazone 
B. Ethacrynic Acid
C. Esomeprazole 
D. Sulbactam
E. A & B

Answer: C. Esomeprazole

04. An indirect-acting adrenergic agonist is following?
A. Clonidine
B. Albuterol
C. Amphetamine
D. Acetylcholine
E. A & B

Answer: C. Amphetamine

05. Which one of the following drugs is used to treat asthma?
A. Hydrochlorothiazide  
B. Repaglinide  
C. Theophylline 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: C. Theophylline 

06. Rapid Acting Insulin is one of the following?
A. Glulisine 
B. Regular
C. NPH 
D. Glargine 

Answer: Glulisine

07. Which of the following drug belongs to H2 histamine receptor blocker?
A. Niacin
B. Cefoxitin 
C. Glimepiride  
D. Famotidine 
E. Oxacillin

Answer: D. Famotidine 

08. Intermediate Acting Insulin is one of the following?
A. Lispro 
B. NPH (neutral Protamine hagedorn)
C. Glargine
D. Detemir 

Answer: B. NPH (neutral Protamine hagedorn)

09. A drug that belongs to proton pump inhibitor  is one of the following?
A. Rosiglitazone 
B. Ethacrynic Acid
C. Lansoprazole 
D. Sulbactam
E. A & B

Answer: C. Lansoprazole

05. Which one of the following drugs treatment usually causes a decrease in intestinal flora?
A. Calcium supplements 
B. Diuretics 
C. Antibiotics 
D. A & B
E.  All of the above 

Answer: C. Antibiotics 

06. Which one of the following drugs is a inhibitors of the P-GP (glycoprotein) efflux pumps?
A. Linezolid
B. Digoxin 
C. Amiodarone 
D. A & B
E. All of the above 

Answer: C. Amiodarone 


07. Which one of the following drugs is a Substrate of the P-GP (glycoprotein) efflux pumps?
A. Erythromycin 
B. Digoxin 
C. Amiodarone 
D. A & B
E. All of the above 

Answer: B. Digoxin 

08. Which of the following statements about the use of aminoglycoside is wrong?
A. cross the placental barrier
B. Bind to 50S subunit
C. Causes ototoxicity
D. Accumulate in renal cortex
E. Accumulate in endolymph and perilymph


Answer: B. Bind to 50S subunit

09. 5-FdUMP a false nucleotide inhibits thymidylate synthetase decreasing thymidylic acid(an essential DNA component) is MOA of following drug?
A. Nystatin
B. Ketoconazole
C. Flucytosine
D. Amphotericin B


Answer: C. Flucytosine
5-fluorodeoxyuridine 5'-monophosphate.

10. Which one of the following drugs has a synergistic effect with Flucytosine?
A. Nystatin
B. Amphotericin B
C. Caspofungin
D. Griseofulvin


Answer: B. Amphotericin B

11. When a intravascular clot started floating in the blood termed as one of the following option?
A. Embolus
B. Thrombus
C. Coagulation
D. All of above


Answer: A. Embolus

12. A drug that is dispersed throughout the body and more than 10% enters the bone matrix and leaves slowly?
A. Fomivirsen 
B. Acyclovir 
C. Foscarnet 
D. Cidofovir 
E. Gancyclovir

Answer: C. Foscarnet

13. Ototoxicity is caused by one of the following drugs when used with aminoglycosides?
A. Vancomycin
B. Aztreonam
C. Imipenem
D. Meropenem


Answer: A. Vancomycin

14. Which one of the following statements about the use of Griseofulvin is wrong?
A. for infection of Nails
B. inhibit fungal mitosis
C. Reduce cytochrome P450 activity
D. it's only fungistatic


Answer: C. Reduce cytochrome P450 activity
It induces hepatic cytochrome P450 activity.

15. A drug that has produced bleeding in warfarin-treated patients even when applied topically is following?
A. Clotrimazole
B. Butoconazole
C. Terconazole
D. Miconazole


Answer: D. Miconazole
Miconazole inhibits the metabolism of Warfarin leading to bleeding in patients treated by warfarin Even when applied topically.

16. Which one of the following drugs inhibits the binding of ADP to its receptor on platelets irreversibly leading to inhibiting the activation of the GP IIb/IIIa receptor?
A. Ticlopidine 
B. Clopidogrel
C. Aspirin
D. A & B
E. All of the above

Answer: D. A & B

17. Cotransport of Sodium with the choline into the cholinergic neuron by using an energy-dependent Carrier system is blocked by the following drug?
A. Botulinum Toxin
B. Spider Venom
C. Pirenzepine
D. Hemicholinium
E. Edrophonium

Answer: D. Hemicholinium ( choline use energy dependent carrier system because choline has a quaternary nitrogen and carries permanent positive charge thus cannot diffuse through membrane. This uptake is a rate limiting step.

18. Excess release of Acetylcholine from the synaptic vesicles into the synaptic gap is caused by?
A. Botulinum Toxin
B. Spider Venom
C. Pirenzepine
D. Hemicholinium
E. Edrophonium

Answer: B. Spider Venom


19. What is the function of Botulinum Toxin in Acetylcholine synthesis?
A. Hydrolyzation of Acetylcholine
B. Transport of choline inhibition
C. Block the release of Acetylcholine to muscarinic
D. Release of neurotransmitters in vesicles
E. Inhibit uptake of Acetylcholine

Answer: C. Block the release of Acetylcholine

20. Which one of the following drugs is used to reduce the fluid accumulation in the lungs to improve oxygenation and heart function?
A. Hydrochlorothiazide
B. Furosemide
C. Acetazolamide
D. Chlorthalidone

Answer: B. Furosemide

21. Which one of the following drugs binds with bile acid and reduces its absorption?
A. Tetracycline 
B. Ciprofloxacin 
C. Rabeprazole
D. Cholestyramine 
E. All of the above 

Answer: D. Cholestyramine 

22. Parasympathetic preganglionic fibers arise from sacral region S2 to S4 as well as cranial nerve III, VII, IX and X. Cranial nerve IX called?

A. Oculomotor

B. Facial 

C. Glossopharyngeal

D. Vagus

Answer: C. Glossopharyngeal

A. Oculomotor III

B. Facial VII

C. Glossopharyngeal IX

D. Vagus X