PHARMACOLOGY QUIZZES 31 | Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug belongs to penicillins?
A. Niacin
B. Dicloxacillin 
C. Fenofibrate
D. Ezetimibe
E. Cefadroxil 

Answer: B. Dicloxacillin 

02. Which one of the following drugs is a Cephalosporin drug?
A. Niacin
B. Cefaclor
C. Ampicillin 
D. Ezetimibe
E. Oxacillin

Answer: B. Cefaclor

03. A drug that belongs to Monobactams is one of the following?
A. Niacin
B. Aztreonam
C. Cefazolin 
D. Ezetimibe
E. Imipenem

Answer: B. Aztreonam

04. Which one of the following drugs is a Carbonic anhydrase Diuretics drug?
A. Chlorthalidone
B. Bumetanide
C. Amiloride
D. Acetazolamide

Answer:. D. Acetazolamide

05. Adefovir belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: A. Antiviral 

06. Tenofovir belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: A. Antiviral  

07. Cefotaxime belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: D. Antibiotics  

08. Oseltamivir belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: A. Antiviral

09. Which one of the following drugs is a mixed amebicide luminal and systemic activity?
A. Metronidazole
B. Tinidazole
C. Paromomycin
D. A & B
E. All of the above

Answer: D. A & B

10. Which one of the following drugs is a luminal amebicide drug?
A. Paromomycin
B. Lodoquinol
C. Metronidazole
D. A & B 
E. All of the above

Answer: D. A & B

11. Therapeutic uses of PGE1 are all except:

a. MTP
b. Impotence
c. Primary pulmonary hypertension
d. Patent ductus arteriosus maintenance 

Answer: c. Primary pulmonary hypertension
AlprostadiL(PGE1) is used for patency of ductus, and impotence
MIsoprostol (PGE1) for abortions
epoprostenol (PGI2) ANALOGUE USED PRIMARY PULMONARY HYPERTENSION

12. When treating a patient chronically for hypertension, which of the following drug will cause maximum orthostatic hypertension:

a. Guanethidine

b. Propranolol

c. Prazosin

d. clonidine

Answer: a. Guanethidine
Guanethidine...will continue to coz orthostatic hypotension, even on chronic treatment. Prazosin leads to orthostatic hypotension, but only in the early doses known as first-dose hypotension.

13. A diabetic patient with bilateral renal artery stenosis requires antihypertensive therapy, most appropriate drug will be:
a. Chlorthiazide
b. Furosemide
c. Amlodipine
d. enalapril
e. metoprolol

Answer: C. Amlodipine
c. amlodipine bcoz ace inhibitor should never be given in stenosed renal artery. chlorothiazide increases blood glucose level and metoprolol will further decrease renal blood flow in the already stenosed renal artery.

14. Which one of the following drugs causes lithiasis?
A. Cholestyramine 
B. Cefaclor
C. Ampicillin 
D. Fenofibrate 
E. Oxacillin

Answer: D. Fenofibrate 
Because fenofibrate increases biliary cholesterol excretion, there's a predisposition to the formation of gallstones.

15. Which one of the following drugs blocks the ability of tubulin to polymerize to form microtubules?
A. Paclitaxel
B. Docetaxel
C. Melphalan
D. Vincristine
E. Dacarbazine


Answer: D. Vincristine

16. A 3-year-old girl consumes 15 325mg aspirin tablets. The initial acid-base disturbance that would be expected to be observed in this patient is:
a) Metabolic acidosis
b) Metabolic alkalosis
c) Respiratory acidosis
d) Respiratory alkalosis


Answer: D. Respiratory alkalosis
The answer is D, respiratory alkalosis. In the case of salicylate overdose, respiratory alkalosis occurs early (INITIALLY) followed later on by Metabolic acidosis. Respiratory acidosis and metabolic alkalosis do not occur.


17. A drug completely blocks Na channels in nerves. Which one of the following effects on the action potential would it expect to produce?
a) Block the occurrence of action potentials
b) Increase the rate of rising of the upstroke of the action potential
c) Shorten the absolute refractory period
d) Abolish the hyperpolarizing afterpotential
e) Increase the Na equilibrium potential


Answer: A. block the occurrence of action potentials
complete blockage of the Na channels would prevent action potential. The upstroke of the action potential depends on the entry of Na into the cell through these channels and therefore it would also be abolished. 
The absolute Refractory period would be lengthened because it is based on the availability of Na Channels. 
The hyperpolarizing afterpotential is dependent on the K permeability
The Na equilibrium potential is calculated from the Nernst equation.

18. Which of the following Drugs prolong the QTc interval?

A. Sotalol 
B. Moxifloxacin
C. Amiodarone
D. A & B
E. All of the above 

Answer: E. All of the above

19. Which one of the following drugs increases the reabsorption of calcium?
A. Spironolactone 
B. Hydrochlorothiazide
C. Triamterene
D. Furosemide

Answer: B. Hydrochlorothiazide

20. A drug used to block the tubular secretion of penicillin and sometimes used to increase the level of antibiotics?
A. Colchicine
B. Sulfinpyrazone
C. Probenecid
D. Allopurinol


Answer: C. Probenecid

21. Which drug is useful in treating sinus bradycardia?

A. Atropine

B. Cisatracurium

C. Neostigmine

D. Succinyicholine

Answer: A. Atropine 

A. Sinus bradycardia is a condition where

the heart rate is below normal and most often caused by

increased vagal tone (increased release of ACh in the sino.

atrial [SA] node that acts on muscarinic receptors to reduce

neart rate). A muscarinic antagonist such as atropine is

useru in this situation to bring the heart rate back to normal.

Succinylcholine and cisatracurium are nicolnic antagonists

and have no effect on muscarinic receptors in the SA node.

Neostigmine is a cholinesterase inhibitor and can worsen

bradycardia by increasing the level of ACh in the SA node.