A. Methyl cellulose
B. Atorvastatin
C. Nizatidine
D. Ezetimibe
E. Indanyl carbenicillin
Answer: A. Methyl cellulose
02. Cephalexin belongs to the class of following drugs?
A. Antiviral
B. Antipyretic
C. Antiprotozoal
D. Antibiotics
E. Anti malaria
Answer: D. Antibiotics
04. Which of the following drug is a part of drugs for osteoporosis?
A. Alendronate
B. Rabeprazole
C. Acetazolamide
D. Furosemide
E. A & B
Answer: A. Alendronate
05. A drug that act as laxative is one of the following?
A. Bumetanide
B. Furosemide
C. Sodium phosphate
D. Sulbactam
E. A & B
Answer: C. Sodium phosphate
06. CLASS II drugs of the Antiarrhythmic drugs interfere with one of the following options?
A. Beta adrenoceptors Blockers
B. K+ channel blockers
C. Ca+ channel blockers
D. Na+ channel blockers
Answer: A. Beta adrenoceptors blockers
07. Fluconazole belongs to the class of following drugs?
A. Antiviral
B. Antipyretic
C. Antiprotozoal
D. Antibiotics
E. Antifungal
Answer: E. Antifungal
08. In case of rising blood pressure, which one of the following neurotransmitter agents is normally released in the sinoatrial node of the heart?
a) Acetylcholine
b) Dopamine
c) Nor-epinephrine
d) Glutamate
e) Epinephrine
Answer: a) Acetylcholine
a) Acetylcholine
b) Dopamine
c) Nor-epinephrine
d) Glutamate
e) Epinephrine
Answer: a) Acetylcholine
09. Which one of the following drugs is directly Acting adrenergic Agonist on the Beta-1 receptor?
A. Salbutamol
B. Dobutamine
C. Isoproterenol
D. Terbutaline
E. Romifidine
Answer: B. Dobutamine
Dobutamine is a direct-acting adrenergic Agonist on the Beta-1 receptor. Act by increasing the Heart rate and cardiac output. because the Beta-1 receptor is present in Cardiac muscles they are activated by Dobutamine. The inotropic effect, An increase in Cardiac muscle contraction is called Inotropic. While you know Muscles contract in presence of Calcium concentration in the Cytoplasm.
On the other hand, the negative inotropic effect is a decrease in the Contraction of cardiac muscles is called NEGATIVE INOTROPIC EFFECT.
A positive Chronotropic Effect is an increase in the Heart rate. While Negative Chronotropic Effect decreases the Heart rate.
A. Salbutamol
B. Dobutamine
C. Isoproterenol
D. Terbutaline
E. Romifidine
Answer: B. Dobutamine
Dobutamine is a direct-acting adrenergic Agonist on the Beta-1 receptor. Act by increasing the Heart rate and cardiac output. because the Beta-1 receptor is present in Cardiac muscles they are activated by Dobutamine. The inotropic effect, An increase in Cardiac muscle contraction is called Inotropic. While you know Muscles contract in presence of Calcium concentration in the Cytoplasm.
On the other hand, the negative inotropic effect is a decrease in the Contraction of cardiac muscles is called NEGATIVE INOTROPIC EFFECT.
A positive Chronotropic Effect is an increase in the Heart rate. While Negative Chronotropic Effect decreases the Heart rate.
10. Eplerenone half-life is following?
A. 3-5 Hour
B. 7-9 Hour
C. 10-12 Hour
D. 15 Hour
E. 24 Hour
Answer: A. 3-5 Hour
11. Disulfiram like reactions and thrombocytopenia are associated with the following?
A. Glimepiride
B. Tolbutamide
C. Acarbose
D. Metformin
Answer: B. Tolbutamide
These adverse effects are associated with first-generation sulfonylureas.
12. Following statements about Glimepiride is incorrect?
A. 2nd generation sulfonylurea
B. Reduce hepatic glucose output
C. Stimulates secretion of insulin
D. Causes hypoglycemia
E. Unexplained Weight loss occurs
Answer: E. unexplained Weight loss occurs
Sulfonylureas cause an unexplained weight gain during the therapy.
13. One Of the following structures, which do not respond to β-adrenergic receptor stimulation?
a) Atrioventricular (AV) node
b) Bronchial muscle
c) Smooth muscles of blood vessels
d) Radial muscle of the iris
e) Sinoatrial (SA) node
Answer: d) Radial muscle of the iris
14. Which one of the following share the same pharmacology, mechanism of action, chemistry, and immunologic characteristics with cephalosporin, monobactams, carbapenems & beta-lactamase inhibitors
A. dalbavancin
B. daptomycin
C. telavancin
D. penicillin
Answer: D. penicillin
15. Antihyperlipidemic drugs are used to control cholesterol levels in the body. By using these drugs patients have the most common side effects?
A. Increased blood pressure
B. Neurological problems
C. Mania
D. GIT problems
E. Heart palpitations
Answer: D. GIT problems
Also causes liver transaminase elevation except bile acid sequestrants.
16. Worsening heart failure is the adverse effect of the following drug?
A. Rosiglitazone
B. Acarbose
C. Miglitol
D. Metformin
E. Glyburide
Answer: A. Rosiglitazone
17. Muscle Pain and Myopathy is the adverse effect of?
A. Glyburide
B. Simvastatin
C. Metformin
D. Acarbose
E. Metoprolol
Answer: B. Simvastatin
18. The activation of muscarinic receptors in bronchiolar smooth muscle is associated with
a) Activation of adenylyl cyclase
b) Decrease in CAMP formation mediated by G-proteins
c) Increase in IP3 and DAG
d) Inhibition of protein kinase C
e) Opening of Na/K cation channels
Answer: c) Increase in IP3 and DAG
19. A patient requires mild cholinomimetic stimulation following surgery .physostigmine and bethanechol in small doses have significantly different effects on which one of the following?
a) Gastric secretion
b) Neuromuscular junction
c) Salivary glands
d) Sweat glands
e) Ureteral tone
Answer: b) Neuromuscular junction
20. One of the following statements about the use of Phentolamine is wrong?
A. Action lasts for 4 hours
B. Causes reversal of epinephrine
C. Used for pheochromocytoma
D. produce non-competitive Alpha receptors blockage
E. Produces postural hypotension
Answer: D. Produce non-competitive Alpha receptors blockage
16. Worsening heart failure is the adverse effect of the following drug?
A. Rosiglitazone
B. Acarbose
C. Miglitol
D. Metformin
E. Glyburide
Answer: A. Rosiglitazone
17. Muscle Pain and Myopathy is the adverse effect of?
A. Glyburide
B. Simvastatin
C. Metformin
D. Acarbose
E. Metoprolol
Answer: B. Simvastatin
18. The activation of muscarinic receptors in bronchiolar smooth muscle is associated with
a) Activation of adenylyl cyclase
b) Decrease in CAMP formation mediated by G-proteins
c) Increase in IP3 and DAG
d) Inhibition of protein kinase C
e) Opening of Na/K cation channels
Answer: c) Increase in IP3 and DAG
19. A patient requires mild cholinomimetic stimulation following surgery .physostigmine and bethanechol in small doses have significantly different effects on which one of the following?
a) Gastric secretion
b) Neuromuscular junction
c) Salivary glands
d) Sweat glands
e) Ureteral tone
Answer: b) Neuromuscular junction
20. One of the following statements about the use of Phentolamine is wrong?
A. Action lasts for 4 hours
B. Causes reversal of epinephrine
C. Used for pheochromocytoma
D. produce non-competitive Alpha receptors blockage
E. Produces postural hypotension
Answer: D. Produce non-competitive Alpha receptors blockage
21. Which of the following is the adverse effect of Trifluridine?
A. Palpebral Edema
B. Weight loss
C. Accomulation of fate at neck
D. Rash on skin
E. Hyphosphatemia
Answer: A. Palpebral (Eyelid) edema
It's a flourinated pyrimidine nucleoside analog antiviral drug having short life necessitiates to apply frequently used in the treatment of HSV-1 and HSV-2 and vaccina virus. Restricted to topical ophthalmic preparation. Toxic for systemic use.
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