MEDICOLOGY: PHARMACOLOGY QUIZZES 04 | Multiple Choice Questions| Medical Exam Preparations

Thursday, January 13, 2022

PHARMACOLOGY QUIZZES 04 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs belongs to Antidiarreals?
A. Methyl cellulose 
B. Atorvastatin
C. Nizatidine 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: A. Methyl cellulose  

02. Cephalexin belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: D. Antibiotics 

04. Which of the following drug is a part of drugs for osteoporosis?
A. Alendronate
B. Rabeprazole
C. Acetazolamide 
D. Furosemide 
E. A & B

Answer: A. Alendronate

05. A drug that act as laxative is one of the following?
A. Bumetanide
B. Furosemide 
C. Sodium phosphate 
D. Sulbactam
E. A & B

Answer: C. Sodium phosphate 

06. CLASS II drugs of the Antiarrhythmic drugs interfere with one of the following options?
A. Beta adrenoceptors Blockers
B. K+ channel blockers
C. Ca+ channel blockers
D. Na+ channel blockers

Answer: A. Beta adrenoceptors blockers

07. Fluconazole belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Antifungal  

Answer: E. Antifungal 

08. In case of rising blood pressure, which one of the following neurotransmitter agents is normally released in the sinoatrial node of the heart? 
a) Acetylcholine
b) Dopamine
c) Nor-epinephrine
d) Glutamate
e) Epinephrine 

Answer: a) Acetylcholine

09. Which one of the following drugs is directly Acting adrenergic Agonist on the Beta-1 receptor?
A. Salbutamol
B. Dobutamine
C. Isoproterenol
D. Terbutaline
E. Romifidine

Answer: B. Dobutamine
Dobutamine is a direct-acting adrenergic Agonist on the Beta-1 receptor. Act by increasing the Heart rate and cardiac output.  because the Beta-1 receptor is present in Cardiac muscles they are activated by Dobutamine. The inotropic effect, An increase in Cardiac muscle contraction is called Inotropic. While you know Muscles contract in presence of Calcium concentration in the Cytoplasm. 
On the other hand, the negative inotropic effect is a decrease in the Contraction of cardiac muscles is called NEGATIVE INOTROPIC EFFECT.
A positive Chronotropic Effect is an increase in the Heart rate. While Negative Chronotropic Effect decreases the Heart rate.

10. Eplerenone half-life is following?
A. 3-5 Hour
B. 7-9 Hour
C. 10-12 Hour
D. 15 Hour
E. 24 Hour

Answer: A. 3-5 Hour

11. Disulfiram like reactions and thrombocytopenia are associated with the following?
A. Glimepiride 
B. Tolbutamide
C. Acarbose
D. Metformin 

Answer: B. Tolbutamide 
These adverse effects are associated with first-generation sulfonylureas.

12. Following statements about Glimepiride is incorrect?
A. 2nd generation sulfonylurea
B. Reduce hepatic glucose output 
C. Stimulates secretion of insulin 
D. Causes hypoglycemia 
E. Unexplained Weight loss occurs 

Answer: E. unexplained Weight loss occurs 
Sulfonylureas cause an unexplained weight gain during the therapy.

13. One Of the following structures, which do not respond to β-adrenergic receptor stimulation?
a) Atrioventricular (AV) node
b) Bronchial muscle
c) Smooth muscles of blood vessels
d) Radial muscle of the iris
e) Sinoatrial (SA) node

Answer: d) Radial muscle of the iris

14. Which one of the following share the same pharmacology, mechanism of action, chemistry, and immunologic characteristics with cephalosporin, monobactams, carbapenems & beta-lactamase inhibitors
A. dalbavancin
B. daptomycin
C. telavancin
D. penicillin

Answer: D. penicillin

15. Antihyperlipidemic drugs are used to control cholesterol levels in the body. By using these drugs patients have the most common side effects?
A. Increased blood pressure
B. Neurological problems
C. Mania 
D. GIT problems
E. Heart palpitations

Answer: D. GIT problems
Also causes liver transaminase elevation except bile acid sequestrants.

16. Worsening heart failure is the adverse effect of the following drug?
A. Rosiglitazone
B. Acarbose
C. Miglitol
D. Metformin
E. Glyburide

Answer: A. Rosiglitazone

17. Muscle Pain and Myopathy is the adverse effect of?
A. Glyburide
B. Simvastatin
C. Metformin
D. Acarbose
E. Metoprolol

Answer: B. Simvastatin

18. The activation of muscarinic receptors in bronchiolar smooth muscle is associated with
a) Activation of adenylyl cyclase
b) Decrease in CAMP formation mediated by G-proteins
c) Increase in IP3 and DAG
d) Inhibition of protein kinase C
e) Opening of Na/K cation channels

Answer: c) Increase in IP3 and DAG

19. A patient requires mild cholinomimetic stimulation following surgery .physostigmine and bethanechol in small doses have significantly different effects on which one of the following?
a) Gastric secretion
b) Neuromuscular junction
c) Salivary glands
d) Sweat glands
e) Ureteral tone

Answer: b) Neuromuscular junction

20. One of the following statements about the use of Phentolamine is wrong?
A. Action lasts for 4 hours
B. Causes reversal of epinephrine
C. Used for pheochromocytoma
D. produce non-competitive Alpha receptors blockage
E. Produces postural hypotension

Answer: D. Produce non-competitive Alpha receptors blockage

21. Which of the following is the adverse effect of Trifluridine?
A. Palpebral Edema
B. Weight loss 
C. Accomulation of fate at neck 
D. Rash on skin
E. Hyphosphatemia 

Answer: A. Palpebral (Eyelid) edema
It's a flourinated pyrimidine nucleoside analog antiviral drug having short life necessitiates to apply frequently used in the treatment of HSV-1 and HSV-2 and vaccina virus. Restricted to topical ophthalmic preparation. Toxic for systemic use.

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