PHARMACOLOGY QUIZZES 11| Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug is a beta-blocker drug?
A. Amlodipine
B. Atenolol
C. Captopril
D. Losartan
E. Methyldopa

Answer: B. Atenolol

02. Which of the following drug is an ACE inhibitor drug?
A. Amlodipine
B. Atenolol
C. Captopril
D. Losartan
E. Methyldopa

Answer: C. Captopril

03. Which one of the following drugs is CLASS l Antiarrhythmic drug?
A. Disopyramide 
B. Esmolol 
C. Amiodarone
D. Diltiazem

Answer: A. Disopyramide

04. Infection in the body causes one of the following issues?
A. High Blood pressure 
B. Fever 
C. Aids
D. Headache 

Answer: B. Fever

05. Which one of the following drugs is a depolarizing neuromuscular blocking drug?
A. Tubocurarine
B. Physostigmine
C. Succinylcholine
D. Gentamicin

Answer: C. Succinylcholine

06. Pioglitazone is used to treat one of the following diseases?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria  

Answer: C. Diabetes

07. Ceftibuten belongs to the class of the following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: D. Antibiotics

08. Which one of the following drugs is a systemic amebicide drug?
A. Chloroquine
B. Metronidazole
C. Paromomycin
D. Tinidazole


Answer: A. Chloroquine

09. Which one of the following drugs belongs to 1st generation Cephalosporins?
A. Cefaclor
B. Cefazolin
C. Cefdinir
D. Cefepime

Answer: B. Cefazolin

10. Esomeprazole is used to treat one of the following diseases?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria  

Answer: D. Stomach Ulcers

11. The action of the drug is increased when given in the presence of another drug called
A. Agonism
B. Antagonism
C. Synergism
D. Idiosyncrasy
E. Teratogenicity

Answer: C. Synergism, is drug Action is increased when given in the presence of another drug.
Other term's
Antagonism is a term in which antagonists decrease the Action of other drugs.
Agonism is an agonist which produces a biological response by binding to the receptor.
Teratogenicity, certain drugs when given in pregnancy cross the placenta and are harmful to the fetus.

Idiosyncratic reaction: Type B ADRs, unexpected, non dose related ADRs e.g carcinogenic and teratogenic effects.

12. Mechanism of action of Nicotinic Acid is?
A. Lipoprotein lipase activator
B. Bile acid sequestrants
C. Inhibitor of triglyceride synthesis and lipolysis
D. HMG-CoA reductase inhibitors
E. Production of Glucose

Answers: C. Inhibitor of triglyceride synthesis and lipolysis
5. Colestipol, along with cholestyramine, colesevelam resins are used as Bile acid sequestrant antihyperlipidemic drugs. These resins are positively charged in the small intestine to bind with the negatively charged bile acid which are reabsorbed from the intestine to the liver and then removed from the body in the fecal matter. Because cholesterol is needed to synthesize Bile acid and extra cholesterol is present in the Low-Density Lipoproteins (LDL) then the Liver signals the LDL receptor to bring LDL circulating in the bloodstream to get cholesterol from this LDL to synthesize Bile acid.
Other Options
 Omeprazole and Esomeprazole is Proton Pump Inhibitor by block the H² receptor to decrease gastric acid secretion. ( Proton Pump Inhibitor H+/K+-ATPase).
Fenofibrate is a Fabric Acid derivative along with other drugs Clofibrate, Gemfibrozil. These agents Reduce the VLDL in the blood by Lipoprotein lipase and enhance the production of HDL by producing Apolipoprotein to increase HDL levels in the blood. 
Lovastatin is an HMG-CoA reductase inhibitor. The Liver synthesizes Cholesterol from acetyl Co-enzyme A by converting hydroxymethylglutaryl-CoA to mevalonate. These agents like Lovastatin compete with the HMG-COA to stop its binding with reductase thus preventing the synthesis of mevalonate that is required to synthesize Cholesterol.

Answer. 3. Inhibitor of triglyceride synthesis and lipolysis, Nicotinic Acid or Niacin lowers the number of VLDL and LDL by reducing the liver triglycerides synthesis and by increasing uptake of VLDL by hepatocytes thus resulting decrease in the number of VLDL and LDL. This leads to an increase in the number of HDL. Niacin is used for hypertriglyceridemia.

These drugs Also causes liver transaminase elevation except bile acid sequestrants.

13. Half-Life of Hydralazine is following?
A. 30 Minutes
B. 1 Hour
C. 2-3 Hour
D. 5-7 Hour
E. 10 Hour

Answer: C. 2-3 Hour

15. Which one of the following symptoms is linked with the overdose of the Ganglion blocker drug?
A. Increased blood pressure
B. Mydriasis
C. Bradycardia
D. Increased Sweating
E. Increased bowel movement

Answer: B. Mydriasis
Because the pupil and the sinoatrial node are dominated by the Parasympathetic system when the sympathetic and Parasympathetic systems are blocked by ganglion blocker drugs. leading to tachycardia and Mydriasis.

17. An Ophthalmic solution causes Mydriasis. it has a duration of action of 24 hours?
A. Atropine
B. Tropicamide
C. Cyclopentolate
D. Scopolamine
E. Ipratropium

Answer: C. Cyclopentolate

18. GP IIb/IIa receptors are present on?
A. Erythrocytes 
B. Platelets
C. Leukocytes 
D. Neutrocytes
E. All of the above 

Answer: Platelets

19. A disease in which women first exhibit elevated plasma glucose levels during pregnancy is called?
A. Type 1 diabetes mellitus
B. Type 2 diabetes mellitus
C. Gestational diabetes mellitus
D. Pregnancy diabetes mellitus

Answer: C. Gestational diabetes mellitus

Insulin is DOC in pregnancy while oral hypoglycaemic agents result in hypoglycemia in neonates.

20. Which of the following drugs converted to 5-phosphate derivatives firstly?
A. Risedronate
B. Ribavirin 
C. Acetazolamide 
D. Furosemide 
E. A & B

Answer: B. Ribavirin

ADRs: Teratogenic effect and dose dependent transient anemia.

Elevated Bilirubin.