A. Amlodipine
B. Atenolol
C. Captopril
D. Losartan
E. Methyldopa
Answer: B. Atenolol
02. Which of the following drug is an ACE inhibitor drug?
A. Amlodipine
B. Atenolol
C. Captopril
D. Losartan
E. Methyldopa
Answer: C. Captopril
03. Which one of the following drugs is CLASS l Antiarrhythmic drug?
A. Disopyramide
B. Esmolol
C. Amiodarone
D. Diltiazem
Answer: A. Disopyramide
04. Infection in the body causes one of the following issues?
A. High Blood pressure
B. Fever
C. Aids
D. Headache
Answer: B. Fever
05. Which one of the following drugs is a depolarizing neuromuscular blocking drug?
A. Tubocurarine
B. Physostigmine
C. Succinylcholine
D. Gentamicin
Answer: C. Succinylcholine
06. Pioglitazone is used to treat one of the following diseases?
A. Viral infection
B. Blood pressure
C. Diabetes
D. Stomach Ulcer
E. Malaria
Answer: C. Diabetes
07. Ceftibuten belongs to the class of the following drugs?
A. Antiviral
B. Antipyretic
C. Antiprotozoal
D. Antibiotics
E. Anti-malaria
Answer: D. Antibiotics
08. Which one of the following drugs is a systemic amebicide drug?
A. Chloroquine
B. Metronidazole
C. Paromomycin
D. Tinidazole
Answer: A. Chloroquine
09. Which one of the following drugs belongs to 1st generation Cephalosporins?
A. Cefaclor
B. Cefazolin
C. Cefdinir
D. Cefepime
Answer: B. Cefazolin
10. Esomeprazole is used to treat one of the following diseases?
A. Viral infection
B. Blood pressure
C. Diabetes
D. Stomach Ulcer
E. Malaria
Answer: D. Stomach Ulcers
11. The action of the drug is increased when given in the presence of another drug called
A. Agonism
B. Antagonism
C. Synergism
D. Idiosyncrasy
E. Teratogenicity
Answer: C. Synergism, is drug Action is increased when given in the presence of another drug.
Other term's
Antagonism is a term in which antagonists decrease the Action of other drugs.
Agonism is an agonist which produces a biological response by binding to the receptor.
Teratogenicity, certain drugs when given in pregnancy cross the placenta and are harmful to the fetus.
Idiosyncratic reaction: Type B ADRs, unexpected, non dose related ADRs e.g carcinogenic and teratogenic effects.
12. Mechanism of action of Nicotinic Acid is?
A. Lipoprotein lipase activator
B. Bile acid sequestrants
C. Inhibitor of triglyceride synthesis and lipolysis
D. HMG-CoA reductase inhibitors
E. Production of Glucose
Answers: C. Inhibitor of triglyceride synthesis and lipolysis
5. Colestipol, along with cholestyramine, colesevelam resins are used as Bile acid sequestrant antihyperlipidemic drugs. These resins are positively charged in the small intestine to bind with the negatively charged bile acid which are reabsorbed from the intestine to the liver and then removed from the body in the fecal matter. Because cholesterol is needed to synthesize Bile acid and extra cholesterol is present in the Low-Density Lipoproteins (LDL) then the Liver signals the LDL receptor to bring LDL circulating in the bloodstream to get cholesterol from this LDL to synthesize Bile acid.
Other Options
Omeprazole and Esomeprazole is Proton Pump Inhibitor by block the H² receptor to decrease gastric acid secretion. ( Proton Pump Inhibitor H+/K+-ATPase).
Fenofibrate is a Fabric Acid derivative along with other drugs Clofibrate, Gemfibrozil. These agents Reduce the VLDL in the blood by Lipoprotein lipase and enhance the production of HDL by producing Apolipoprotein to increase HDL levels in the blood.
Lovastatin is an HMG-CoA reductase inhibitor. The Liver synthesizes Cholesterol from acetyl Co-enzyme A by converting hydroxymethylglutaryl-CoA to mevalonate. These agents like Lovastatin compete with the HMG-COA to stop its binding with reductase thus preventing the synthesis of mevalonate that is required to synthesize Cholesterol.
Answer. 3. Inhibitor of triglyceride synthesis and lipolysis, Nicotinic Acid or Niacin lowers the number of VLDL and LDL by reducing the liver triglycerides synthesis and by increasing uptake of VLDL by hepatocytes thus resulting decrease in the number of VLDL and LDL. This leads to an increase in the number of HDL. Niacin is used for hypertriglyceridemia.
These drugs Also causes liver transaminase elevation except bile acid sequestrants.
13. Half-Life of Hydralazine is following?
A. 30 Minutes
B. 1 Hour
C. 2-3 Hour
D. 5-7 Hour
E. 10 Hour
Answer: C. 2-3 Hour
15. Which one of the following symptoms is linked with the overdose of the Ganglion blocker drug?
A. Increased blood pressure
B. Mydriasis
C. Bradycardia
D. Increased Sweating
E. Increased bowel movement
Answer: B. Mydriasis
Because the pupil and the sinoatrial node are dominated by the Parasympathetic system when the sympathetic and Parasympathetic systems are blocked by ganglion blocker drugs. leading to tachycardia and Mydriasis.
A. Atropine
B. Tropicamide
C. Cyclopentolate
D. Scopolamine
E. Ipratropium
Answer: C. Cyclopentolate
18. GP IIb/IIa receptors are present on?
A. Erythrocytes
B. Platelets
C. Leukocytes
D. Neutrocytes
E. All of the above
Answer: Platelets
A. Type 1 diabetes mellitus
B. Type 2 diabetes mellitus
C. Gestational diabetes mellitus
D. Pregnancy diabetes mellitus
Answer: C. Gestational diabetes mellitus
Insulin is DOC in pregnancy while oral hypoglycaemic agents result in hypoglycemia in neonates.
A. Risedronate
B. Ribavirin
C. Acetazolamide
D. Furosemide
E. A & B
Answer: B. Ribavirin
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