PHARMACOLOGY QUIZZES 23 | Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug is an HMG COA REDUCTASE INHIBITORS (STATINS)?
A. Niacin
B. Rosuvastatin
C. Fenofibrate
D. Ezetimibe
E. Colestipol

Answer: B. Rosuvastatin

02. A drug that belongs to BILE ACID SEQUESTRANTS is one of the following?
A. Niacin
B. Fluvastatin
C. Fenofibrate
D. Ezetimibe
E. Colestipol

Answer: E. Colestipol

03. A drug that belongs to CLASS III?
A. Propafenone (IC)
B. Esmolol
C. Amiodarone
D. Verapamil

Answer: C. Amiodarone

04. A drug that belongs to CLASS III?
A. Quinidine (IA)
B. Atenolol
C. Dronedarone 
D. Verapamil

Answer: C. Dronedarone

05. A drug that is used to treat HIV infections is one of the following?
A. Cladribine
B. Praziquantel 
C. Niclosamide
D. Etidronate
E.  Delavirdine 
Answer: E. Delavirdine

06. A drug that is used to treat Helminthic infections for nematodes is one of the following?
A. Cladribine
B.  Mebendazole
C. Flucytosine
D. Etidronate
E. Itraconazole

Answer: B. Mebendazole

07. Acyclovir is used to treat one of the following diseases?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria
Answer: A. Viral infection   

08. Diltiazem is used to treat one of the following diseases?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria

Answer: B. Blood pressure

09. Disopyramide is an Antiarrhythmic drug of one of the following CLASS?
A. IA
B. IB
C. IC
D. CLASS IV

Answer: A. IA

10. Which one of the following drugs is a macrolide?

A. Erythromycin
B. Tetracyclin
C. Amikacin
D. Linezolid
 
Answer: A. Erythromycin

11. Chemical mediator synthesized by endothelial cells?
A. Thromboxane A2
B. Serotonin 
C. Prostacyclin 
D. ADP
E. PAF

Answer: C. Prostacyclin 

12. Which of the following drug is used for Pulmonary arterial hypertension(PAH)?
A. Lisinopril
B. Eplerenone
C. Losartan
D. Bosentan
E. Diltiazem

Answer: Bosentan

13. A dry cough is the common side effect of which antihypertensive class?
A. ACE inhibitors
B. ARB inhibitors
C. Ca++ channel blockers
D. Alpha receptor blockers
E. Beta-blockers

Answer: A. ACE inhibitors

14. If a person is suffering from high blood pressure and high cholesterol levels which of the following drug is more preferred?
A. Losartan
B. Lisinopril
C. Deltiazam
D. Amlodipine
E. Prazosin

Answer: E.  Prazosin

15. Elevated cytosolic Ca+2 within the platelet causes?
A. Inhibition of platelet granules 
B. Deactivate thromboxane A2 synthesis 
C. Activation of GP IIb/IIIa receptors
D. Release prostacyclin 
E. All of the above 

Answer: C. Activation of GP IIb/IIIa receptors 

16. A 36-year-old male came to an emergency and was diagnosed with paroxysmal supraventricular tachycardia (PSVT). Which of the following drugs would you think is the drug of the first choice in this situation?
A. Adenosine
B. Amiodarone
C. Verapamil
D. Propranolol

Answer: A. Adenosine

17.  A disorder that is characterized by chronic inflammation of GIT mucosa and primarily found in the rectum and colon?
A. Crohn's disease 
B. Ulcerative colitis
C. Irritable bowel syndrome
D. A & B 

Answer: B. Ulcerative colitis 

18.  Hypotension, bradycardia, respiratory depression, and muscle weakness, all unresponsive to neostigmine & atropine, would most likely be because of?
a) Diazoxide
b) Isofluorphate
c) Nicotine
d) Pilocarpine
e) Tubocurarine

Answer: c) Nicotine

19. Which of the following drugs has excellent CNS penetration & used in fungal meningitis except?
A. amphotericin B
B. fluconazole
C. voriconazole
D. posaconazole 

Answer: A. Amphotericin B 

20. Which one of the following statements about the interferons is wrong?
A. Inhibit viral RNA translation 
B. Oral administration more effective 
C. Treat hepatitis B and C
D. Cause flu-like symptoms 
E. Peginterferon injected once weekly 

Answer: B. Oral administration more effective 
Interferon is not active orally and is administered intravenously or subcutaneously.

21. Which of the following drug inhibits the synthesis of mycolic acid, an essential component of the mycobacterial cell wall?
A. rifampin
B. Isoniazid
C. rifabutin
D. rifapentine 

Answer: B. Isoniazid

22. A Direct acting adrenergic agonist that stimulates Alpha receptors on blood vessels that supplies blood to the conjunctiva and nasal mucosa to reduce blood supply to decrease congestion?
A. Clonidine
B. Metaproterenol
C. Oxymetazoline
D. Dobutamine
E. Formoterol

Answer: C. Oxymetazoline

23. Which one of the following drugs binds irreversibly to a site on the 50S subunit of the bacterial ribosome?
A. Erythromycin
B. Amikacin
C. Gentamicin
D. Tobramycin


Answer: A. Erythromycin

24. Which one of the following drugs binds irreversibly to a site on the 50S subunit of the bacterial ribosome?
A. Erythromycin
B. Amikacin
C. Gentamicin
D. Tobramycin


Answer: A. Erythromycin

25. The muscarinic receptor is present on cardiac cells, smooth muscles, Brain & exocrine glands. Which one of the following Muscarinic receptors is present in cardiac cells?
A. M¹
B. M²
C. M³
D. M⁴
E. M⁵

Answer: B. M²

26. Muscarinic receptors are present on cardiac cells, smooth muscles, Brain & exocrine glands. Which one of the following Muscarinic receptors is present in the Bladder?
A. M¹
B. M²
C. M³
D. M⁴
E. M⁵
 
Answer: C. M³

27. A drug that increases the PH of the stomach is following?
A. Sotalol
B. Furosemide 
C. Magnesium hydroxide  
D. Tiludronate
E. A & B

Answer: C. Magnesium hydroxide (Antacid)

28. A drug that increases gastric PH is following?
A. Sotalol
B. Furosemide 
C. Bicarbonate salt
D. Tiludronate
E. A & B

Answer: C. Bicarbonate salt

29. Which of the following proteins are involved in the remodeling of bone?
A. Osteoprotegerin OPG
B. Receptor activator of nuclear factor kappa-B (RANK)
C. Fibronectin
D. A & B
E. All of the above


Answer: D. A & B
Osteoprotegerin works against receptor activator of nuclear factor kappa-B (RANK).
RANK activates the osteoclasts that break down bone (resorption). Osteoprotegerin binds with RANK legend to stop the activity of RANK.

30. A high dose of Imipenem causes following adverse effects?
A. Diarrhea
B. Hypertriglyceridemia
C. Hypersensitivity
D. Seizures

Answer: D. Seizures

31. Beta-Blockers toxicity can be reduced by using the following drugs?
A. Naloxone
B. Labetalol
C. Glucagon 
D. Pyridoxine
E. B & C 

Answer: C. Glucagon Dose: 5-10mg IV bolus followed by 5-10mg/h IV infusion titrated to effect Child dose: 0.15mg/kg IV bolus followed by 0.1 mg/h IV infusion titrated to effect