PHARMACOLOGY QUIZZES 24 | Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug is an HMG COA REDUCTASE INHIBITORS (STATINS)?
A. Niacin
B. Simvastatin
C. Fenofibrate
D. Ezetimibe
E. Colestipol

Answer: B. Simvastatin

02. A drug that belongs to BILE ACID SEQUESTRANTS is one of the following?
A. Niacin
B. Fluvastatin
C. Fenofibrate
D. Ezetimibe
E. Cholestyramine 

Answer: E. Cholestyramine 

03. Which of the following are 2nd generation drugs except?
A. Chlorpheniramine
B. Fexofenadine
C. Ebastine
D. Loratadine
E. Cetirizine

Answer: A. Chlorpheniramine

04. A drug that belongs to CLASS II?
A. Quinidine (IA)
B. Atenolol
C. Amiodarone
D. Verapamil

Answer: B. Atenolol

05. A drug that belongs to CLASS II?
A. Propafenone (IC)
B. Atenolol
C. Amiodarone
D. Verapamil

Answer: A. Propafenone (IC)

06. Currently, three subtypes of histamine receptors are proposed: H₁ and H₂ receptors are found in peripheral tissues, and the central nervous system (CNS), and H3 receptors are found in the CNS. The second messenger pathway that mediates H₁-receptor stimulation is:
A. Activation of sodium (Na+) ion flow into the cell
B. Activation of tyrosine kinases
C. Elevation of Intracellular adenosine 3′,5′-cyclic monophosphate [cyclic AMP (cAMP)]
D. Increased formation of inositol trisphosphate
E. Inhibition of adenylate cyclase activity

Answer: D. Increased formation of inositol trisphosphate

07. Which of the following drugs is used for hepatic viral infections?
A. Ibandronate
B. Oseltamivir  
C. Capecitabine
D. Adefovir
E. Naftifine

Answer: D. Adefovir    

08. Which one of the following drugs belongs to an alkylating agent?
A. Gemcitabine
B. Capreomycin
C. Lamivudine 
D. Chlorambucil
E. Indanyl carbenicillin 

Answer: D. Chlorambucil 

09. Which of the following drugs is used for respiratory virus infections?
A. Ibandronate
B. Amantadine
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Amantadine

10. Which one of the following drugs is 2nd generation fluoroquinolone?
A. Moxifloxacin
B. Levofloxacin
C. Ciprofloxacin
D. Nalidixic acid


Answer: C. Ciprofloxacin

11. Which of the following are the adverse effect of Loop diuretics and Thiazides Except?
A. Metabolic alkalosis
B. Hyponaturaenia
C. Hyperkalaemia
D. Hypokalaemia
E. Hyperuricemia

Answer: C. Hyperkalaemia

12. Which of the following is the adverse effect of  K+ Sparing Diuretics?
A. Metabolic acidosis
B. Hypernaturaenia
C. Hypercalcaemia
D. Hypokalaemia
E. Hyperglycaemia

Answer: A. Metabolic Acidosis

13. Which one of the following interferon drugs has been approved for the treatment of Condylomata acuminate?
A. Interferon-alpha
B. Interferon-Beta
C. Interferon-Gamma
D. A & B
E. All of these 

Answer: Interferon-alpha 

14. A 27-year-old male is advised of acetylsalicylic acid for an ongoing condition. He is most likely to experience:
A. Alleviation of pain by stimulation of prostaglandin synthesis
B. observe the anti-inflammatory Effect of acetaminophen 
C. Less gastric irritation than other salicylates
D. Promotion of platelet aggregation
E. Reduction in elevated body temperature

Answer: E. Reduction in elevated body temperature

15. A disorder which is characterized by chronic inflammation of GIT mucosa and found from mouth to the anus throughout the GIT?
A. Crohn's disease 
B. Ulcerative colitis
C. Irritable bowel syndrome
D. A & B 

Answer: A. Crohn's disease

16. Which one of the following Diuretic drugs prevents the loss of K+ that occurs by giving other diuretics?
A. Loop Diuretics
B. Carbonic anhydrase inhibitors
C. Thiazide Diuretic
D. Potassium-sparing Diuretics

Answer: D. Potassium-sparing Diuretics

17. Which one of the following Clinical features is more common in Crohn's disease as compared to ulcerative colitis?
A. Joint pain
B. Slow onset of disease
C. Fistula formation
D. Abnormal bowel movement

Answer: Fistula formation

18. Which one of the following statements about Quinidine is wrong?
A. Class IV Antiarrhythmic drug
B. prevent sodium influx
C. Has the atropine-like effect
D. Causes torsades de pointes

Answer: A. Class IV Antiarrhythmic drug
It belongs to class IA Antiarrhythmic drugs.

19. A drug promotes renal clearance of Uric Acid by inhibiting the urate-anion exchanger?
A. Colchicine
B. Sulfinpyrazone
C. Allopurinol
D. Sulindac

Answer: B. Sulfinpyrazone

20. Which one of the following statements about the Lamivudine is wrong?
A. A cytosine analog 
B. Inhibitor of HBV DNA polymerase 
C. Inhibitor of HIV reverse transcriptase 
D. Orally not absorbed  
E. Plasma half-life is 9 Hr.

Answer: D. Orally not effective 
Lamivudine is well absorbed orally and distributed widely. All other options are right.