01. Which of the following drug is an HMG COA REDUCTASE INHIBITORS (STATINS)?
A. Niacin
B. Simvastatin
C. Fenofibrate
D. Ezetimibe
E. Colestipol
Answer: B. Simvastatin
02. A drug that belongs to BILE ACID SEQUESTRANTS is one of the following?
A. Niacin
B. Fluvastatin
C. Fenofibrate
D. Ezetimibe
E. Cholestyramine
Answer: E. Cholestyramine
03. Which of the following are 2nd generation drugs except?
A. Chlorpheniramine
B. Fexofenadine
C. Ebastine
D. Loratadine
E. Cetirizine
Answer: A. Chlorpheniramine
04. A drug that belongs to CLASS II?
A. Quinidine (IA)
B. Atenolol
C. Amiodarone
D. Verapamil
Answer: B. Atenolol
A. Niacin
B. Simvastatin
C. Fenofibrate
D. Ezetimibe
E. Colestipol
Answer: B. Simvastatin
02. A drug that belongs to BILE ACID SEQUESTRANTS is one of the following?
A. Niacin
B. Fluvastatin
C. Fenofibrate
D. Ezetimibe
E. Cholestyramine
Answer: E. Cholestyramine
03. Which of the following are 2nd generation drugs except?
A. Chlorpheniramine
B. Fexofenadine
C. Ebastine
D. Loratadine
E. Cetirizine
Answer: A. Chlorpheniramine
04. A drug that belongs to CLASS II?
A. Quinidine (IA)
B. Atenolol
C. Amiodarone
D. Verapamil
Answer: B. Atenolol
05. A drug that belongs to CLASS II?
A. Propafenone (IC)
B. Atenolol
C. Amiodarone
D. Verapamil
Answer: A. Propafenone (IC)
06. Currently, three subtypes of histamine receptors are proposed: H1 and H2 receptors are found in peripheral tissues, and the central nervous system (CNS), and H3 receptors are found in the CNS. The second messenger pathway that mediates H1-receptor stimulation is:
A. Activation of sodium (Na+) ion flow into the cell
B. Activation of tyrosine kinases
C. Elevation of Intracellular adenosine 3′,5′-cyclic monophosphate [cyclic AMP (cAMP)]
D. Increased formation of inositol trisphosphate
E. Inhibition of adenylate cyclase activity
Answer: D. Increased formation of inositol trisphosphate
07. Which of the following drugs is used for hepatic viral infections?
A. Ibandronate
B. Oseltamivir
C. Capecitabine
D. Adefovir
E. Naftifine
Answer: D. Adefovir
08. Which one of the following drugs belongs to an alkylating agent?
A. Gemcitabine
B. Capreomycin
C. Lamivudine
D. Chlorambucil
E. Indanyl carbenicillin
Answer: D. Chlorambucil
09. Which of the following drugs is used for respiratory virus infections?
A. Ibandronate
B. Amantadine
C. Capecitabine
D. Miconazole
E. Naftifine
Answer: B. Amantadine
A. Ibandronate
B. Oseltamivir
C. Capecitabine
D. Adefovir
E. Naftifine
Answer: D. Adefovir
08. Which one of the following drugs belongs to an alkylating agent?
A. Gemcitabine
B. Capreomycin
C. Lamivudine
D. Chlorambucil
E. Indanyl carbenicillin
Answer: D. Chlorambucil
09. Which of the following drugs is used for respiratory virus infections?
A. Ibandronate
B. Amantadine
C. Capecitabine
D. Miconazole
E. Naftifine
Answer: B. Amantadine
10. Which one of the following drugs is 2nd generation fluoroquinolone?
A. Moxifloxacin
B. Levofloxacin
C. Ciprofloxacin
D. Nalidixic acid
Answer: C. Ciprofloxacin
A. Moxifloxacin
B. Levofloxacin
C. Ciprofloxacin
D. Nalidixic acid
Answer: C. Ciprofloxacin
11. Which of the following are the adverse effect of Loop diuretics and Thiazides Except?
A. Metabolic alkalosis
B. Hyponaturaenia
C. Hyperkalaemia
D. Hypokalaemia
E. Hyperuricemia
Answer: C. Hyperkalaemia
A. Metabolic alkalosis
B. Hyponaturaenia
C. Hyperkalaemia
D. Hypokalaemia
E. Hyperuricemia
Answer: C. Hyperkalaemia
12. Which of the following is the adverse effect of K+ Sparing Diuretics?
A. Metabolic acidosis
B. Hypernaturaenia
C. Hypercalcaemia
D. Hypokalaemia
E. Hyperglycaemia
Answer: A. Metabolic Acidosis
A. Metabolic acidosis
B. Hypernaturaenia
C. Hypercalcaemia
D. Hypokalaemia
E. Hyperglycaemia
Answer: A. Metabolic Acidosis
13. Which one of the following interferon drugs has been approved for the treatment of Condylomata acuminate?
A. Interferon-alpha
B. Interferon-Beta
C. Interferon-Gamma
D. A & B
E. All of these
A. Interferon-alpha
B. Interferon-Beta
C. Interferon-Gamma
D. A & B
E. All of these
Answer: Interferon-alpha
14. A 27-year-old male is advised of acetylsalicylic acid for an ongoing condition. He is most likely to experience:
A. Alleviation of pain by stimulation of prostaglandin synthesis
B. observe the anti-inflammatory Effect of acetaminophen
C. Less gastric irritation than other salicylates
D. Promotion of platelet aggregation
E. Reduction in elevated body temperature
Answer: E. Reduction in elevated body temperature
15. A disorder which is characterized by chronic inflammation of GIT mucosa and found from mouth to the anus throughout the GIT?
A. Crohn's disease
B. Ulcerative colitis
C. Irritable bowel syndrome
D. A & B
Answer: A. Crohn's disease
A. Crohn's disease
B. Ulcerative colitis
C. Irritable bowel syndrome
D. A & B
Answer: A. Crohn's disease
16. Which one of the following Diuretic drugs prevents the loss of K+ that occurs by giving other diuretics?
A. Loop Diuretics
B. Carbonic anhydrase inhibitors
C. Thiazide Diuretic
D. Potassium-sparing Diuretics
A. Loop Diuretics
B. Carbonic anhydrase inhibitors
C. Thiazide Diuretic
D. Potassium-sparing Diuretics
Answer: D. Potassium-sparing Diuretics
17. Which one of the following Clinical features is more common in Crohn's disease as compared to ulcerative colitis?
A. Joint pain
B. Slow onset of disease
C. Fistula formation
D. Abnormal bowel movement
Answer: Fistula formation
18. Which one of the following statements about Quinidine is wrong?
A. Class IV Antiarrhythmic drug
B. prevent sodium influx
C. Has the atropine-like effect
D. Causes torsades de pointes
Answer: A. Class IV Antiarrhythmic drug
It belongs to class IA Antiarrhythmic drugs.
19. A drug promotes renal clearance of Uric Acid by inhibiting the urate-anion exchanger?
A. Colchicine
B. Sulfinpyrazone
C. Allopurinol
D. Sulindac
Answer: B. Sulfinpyrazone
20. Which one of the following statements about the Lamivudine is wrong?
A. A cytosine analog
B. Inhibitor of HBV DNA polymerase
C. Inhibitor of HIV reverse transcriptase
D. Orally not absorbed
E. Plasma half-life is 9 Hr.
Answer: D. Orally not effective
Lamivudine is well absorbed orally and distributed widely. All other options are right.
A. Joint pain
B. Slow onset of disease
C. Fistula formation
D. Abnormal bowel movement
Answer: Fistula formation
18. Which one of the following statements about Quinidine is wrong?
A. Class IV Antiarrhythmic drug
B. prevent sodium influx
C. Has the atropine-like effect
D. Causes torsades de pointes
Answer: A. Class IV Antiarrhythmic drug
It belongs to class IA Antiarrhythmic drugs.
19. A drug promotes renal clearance of Uric Acid by inhibiting the urate-anion exchanger?
A. Colchicine
B. Sulfinpyrazone
C. Allopurinol
D. Sulindac
Answer: B. Sulfinpyrazone
20. Which one of the following statements about the Lamivudine is wrong?
A. A cytosine analog
B. Inhibitor of HBV DNA polymerase
C. Inhibitor of HIV reverse transcriptase
D. Orally not absorbed
E. Plasma half-life is 9 Hr.
Answer: D. Orally not effective
Lamivudine is well absorbed orally and distributed widely. All other options are right.
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