01. Which one of the following drugs is a Thiazide Diuretic?
A. Chlorthalidone
B. Atorvastatin
C. Fenofibrate
D. Ezetimibe
E. Indanyl carbenicillin
Answer: A. Chlorthalidone
02. Which one of the following drugs belongs to an alkylating agent?
A. Gemcitabine
B. Capreomycin
C. Lamivudine
D. Streptozocin
E. Indanyl carbenicillin
Answer: D. Streptozocin
03. Which of the following drug belongs to Osmotic Diuretic?
A. Niacin
B. Cefoxitin
C. Ampicillin
D. Mannitol
E. Oxacillin
Answer: D. Mannitol
04. A drug that belongs to Loop Diuretics is one of the following?
A. Doripenem
B. Bumetanide
C. Cefazolin
D. Sulbactam
E. A & B
Answer: B. Bumetanide
A. Gemcitabine
B. Capreomycin
C. Lamivudine
D. Streptozocin
E. Indanyl carbenicillin
Answer: D. Streptozocin
03. Which of the following drug belongs to Osmotic Diuretic?
A. Niacin
B. Cefoxitin
C. Ampicillin
D. Mannitol
E. Oxacillin
Answer: D. Mannitol
04. A drug that belongs to Loop Diuretics is one of the following?
A. Doripenem
B. Bumetanide
C. Cefazolin
D. Sulbactam
E. A & B
Answer: B. Bumetanide
05. Which one of the following drugs is a proton pump inhibitor drug?
A. Cimetidine
B. Rabeprazole
C. Sucralfate
D. Misoprostol
A. Cimetidine
B. Rabeprazole
C. Sucralfate
D. Misoprostol
Answer: B. Rabeprazole06. Which one of the following drugs belongs to Second-line drugs used to treat tuberculosis?
A. Aluminium hydroxide
B. Cycloserine
C. Nizatidine
D. Ezetimibe
E. Indanyl carbenicillin
Answer: B. Cycloserine
07. Which of the following drug is a part of drugs as first-line drugs used to treat tuberculosis?
A. Ibandronate
B. Rabeprazole
C. Isoniazid
D. Furosemide
E. A & B
Answer: C. Isoniazid
08. Which one of the following drugs belongs to Second-line drugs used to treat tuberculosis?
A. Aluminium hydroxide
B. Capreomycin
C. Nizatidine
D. Ezetimibe
E. Indanyl carbenicillin
Answer: B. Capreomycin
09. Which of the following drug is a part of drugs as first-line drugs used to treat tuberculosis?
A. Ibandronate
B. Rabeprazole
C. Ethambutol
D. Furosemide
E. A & B
Answer: C. Ethambutol
13. Which of the following drugs has the least CNS side effects?
A. Amantadine
B. Rimantadine
C. Acyclovir
D. Ganciclovir
E. Zidovudine
Answer: B. Rimantadine
14. Liposomal preparation of one of the following drugs decreases the risk of nephrotoxicity?
A. Isoniazid
B. Amphotericin B
C. Ethambutol
D. Nystatin
Answer: B. Amphotericin B (polyene antifungal naturally produced from Streptomyces nodosus) produce porin in fungal cell membrane.
A. Aluminium hydroxide
B. Capreomycin
C. Nizatidine
D. Ezetimibe
E. Indanyl carbenicillin
Answer: B. Capreomycin
09. Which of the following drug is a part of drugs as first-line drugs used to treat tuberculosis?
A. Ibandronate
B. Rabeprazole
C. Ethambutol
D. Furosemide
E. A & B
Answer: C. Ethambutol
10. Mechanism of action of Abciximab is following?
A. Inhibit glycoprotein receptors
B. Inhibit ADP mediation
C. Inhibit COX-1
D. Inhibit COX-2
E. Decrease Calcium levels
Answer: A. Inhibit glycoprotein receptors
A. Inhibit glycoprotein receptors
B. Inhibit ADP mediation
C. Inhibit COX-1
D. Inhibit COX-2
E. Decrease Calcium levels
Answer: A. Inhibit glycoprotein receptors
11. Mechanism of action of Ticlopidine is following?
A. Inhibit glycoprotein receptors
B. Inhibit ADP mediation
C. Inhibit COX-1
D. Inhibit COX-2
E. Decrease Calcium levels
Answer: B. Inhibit ADP mediation
A. Inhibit glycoprotein receptors
B. Inhibit ADP mediation
C. Inhibit COX-1
D. Inhibit COX-2
E. Decrease Calcium levels
Answer: B. Inhibit ADP mediation
12. Mechanism of action of Aspirin is following?
A. Inhibit glycoprotein receptors
B. Inhibit ADP mediation
C. Inhibit COX-1
D. Inhibit COX-2
E. Decrease Calcium levels
Answer: C. Inhibit COX-1
A. Inhibit glycoprotein receptors
B. Inhibit ADP mediation
C. Inhibit COX-1
D. Inhibit COX-2
E. Decrease Calcium levels
Answer: C. Inhibit COX-1
13. Which of the following drugs has the least CNS side effects?
A. Amantadine
B. Rimantadine
C. Acyclovir
D. Ganciclovir
E. Zidovudine
Answer: B. Rimantadine
14. Liposomal preparation of one of the following drugs decreases the risk of nephrotoxicity?
A. Isoniazid
B. Amphotericin B
C. Ethambutol
D. Nystatin
Answer: B. Amphotericin B (polyene antifungal naturally produced from Streptomyces nodosus) produce porin in fungal cell membrane.
ADVs: Fever, renal impairment, hypotension, Thrombophlebitis
15. A 22-year-old man with testicular cancer begins chemotherapy. One week later he develops edema of the legs and eyelids and is also found to have a substantial decrease in bilateral auditory acuity. Which of the following agents is most likely responsible for these adverse effects?
A. Cisplatin
B. Cyclophosphamide
C. Daunorubicin
D. Methotrexate
E. Vincristine
Answer: A. Cisplatin
16. Pins and needles and numbness is the adverse effect of the following drug?
A. Nystatin
B. Isoniazid
C. Ethambutol
D. Streptomycin
Answer: B. Isoniazid
Because Isoniazid enhances the excretion of pyridoxine as well as reduces its activation.
17. Which statement about the Actions of the incretin hormone Glucagon-like peptide-1 is wrong?
A. Increase Glucose-dependent insulin secretion
B. Inhibit inappropriate Glucagon secretion
C. Decrease Beta cells growth
D. Suppress appetite
Answer: C. Decrease Beta cells growth
A. Increase Glucose-dependent insulin secretion
B. Inhibit inappropriate Glucagon secretion
C. Decrease Beta cells growth
D. Suppress appetite
Answer: C. Decrease Beta cells growth
18. Which one of the following drugs decreases endogenous hepatic production of glucose?
A. SitagliptinB. Pioglitazone
C. Acarbose
D. Metformin
Answer: D. Metformin
19. One of the following statements about the use of scopolamine is wrong?
A. Used for Motion sickness
B. Short term memory blocker
C. produce excitement at high doses
D. Belladonna Alkaloid
E. Shorter duration of action as compared to atropine in CNS
Answer: E. Shorter duration of action as compared to atropine in CNS
20. Low doses of one of the following drugs produce sedation, but at high doses it produces excitement?
A. Atropine
B. Physostigmine
C. Scopolamine
D. Pirenzepine
E. Phenylephrine
Answer: C. Scopolamine
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