MEDICOLOGY: PHARMACOLOGY QUIZZES 56 | Multiple Choice Questions| Medical Exam Preparations

Saturday, February 19, 2022

PHARMACOLOGY QUIZZES 56 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is a Meglitinide drug?
A. Hydrochlorothiazide  
B. Repaglinide  
C. Fenofibrate
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: B. Repaglinide 

02. Indirectly acting reversible cholinergic agonist drug?
A. Pilocarpine
B. Acetylcholine
C. Tacrine
D. Echothiophate

Answer: C. Tacrine


03. Which of the following drug belongs to Sulfonylureas?
A. Niacin
B. Cefoxitin 
C. Glimepiride  
D. Urae
E. Oxacillin

Answer: C. Glimepiride 


04. A drug that belongs to thiazolidinediones  is one of the following?
A. Rosiglitazone 
B. Ethacrynic Acid
C. Cefazolin 
D. Sulbactam
E. A & B

Answer: A. Rosiglitazone, Pioglitazone (fluid retention and worsen symptoms of heart failure)

05. Directly acting cholinergic agonist drug?
A. Pilocarpine
B. Acetylcholine
C. Tacrine
D. Echothiophate
E. A & B

Answer: E. A & B


06. A drug used in severe DIGITALIS toxicity is the following drug?
A. DIGIBIND
B. Fomepizole
C. Calcium Gluconate
D. Amyl Nitrate

Answer: A) DIGIBIND

07. A drug is used in severe alcohol poisoning is the following drug?
A. DIGIBIND
B. Fomepizole
C. Calcium Gluconate
D. Amyl Nitrate

Answer: B) FOMEPIZOLE 


08. Which of the following drug are Nonsteroidal antiestrogens?
A. Estrogen
B. Estradiol
C. Estradiol acetate
D. Tamoxifen
E. Exemestane

Answer: D. Tamoxifen

09. Reversible neutropenia and thrombocytopenia is the adverse effect of following drug?
A. Nystatin
B. Amphotericin B
C. Flucytosine
D. Ketoconazole


Answer: C. Flucytosine

10. A drug causes Blockage of the M2 protein ion channel and it's ability to modulate intracellular PH?
A. Amantadine 
B. Vidarabine 
C. Zanamavir 
D. Acyclovir 
E. Lamivudine 

Answer: A. Amantadine

11. Blockage of ɑ1 and ɑ2 adrenergic receptors on the arteriolar beds lead to following?
A. Reduce peripheral resistance 
B. Increase peripheral resistance 
C. Increase renin secretion 
D. Increase renin secretion 
E. None 

Answer: A. Reduce peripheral resistance 

12. The sympathomimetic which may promote diuresis by a direct effect on the kidney is:
A. Isoproterenol 
B. dobutamine
C. norepinephrine
D. dopamine
E. epinephrine

Answer: Dopamine


13. A patient requires quinidine to treat his atrial arrhythmia, which of the following drugs should be administered prior to it to prevent the deleterious effects?
a. Amiodarone 
b. Acetaminophen
c. Digoxin
d. Mexalitine
 
Answer: Digoxin

14. What is the meaning of Dose Dumping phenomenon?
A. Excess release of Insulin 
B. Excess release of gastric acid 
C. Excess release of control released drugs
D. Excess release of glucose 
E.  High dose of IV drugs 

Answer: C. Excess release of control released drugs 

15. A drugs inhibit the urate-anion exchanger in the proximal tubules that mediates urate reabsorption?
A. Probenecid
B. Allopurinol
C. Colchicine
D. Sulindac

Answer: A. Probenecid

16. Most commonly used a diuretic to inhibit the reabsorption of Na+ and Cl- in the distal convoluted tubules resulting in the water retention in the tubules?
A. Chlorothiazide
B. Furosemide
C. Acetazolamide
D. Spironolactone

Answer: A. Chlorothiazide 

17. Topical antifungal drug Nystatin is polyene macrolide much like ________?
A. ketoconazole
B. itraconazole
C. nystatin
D. fluconazole 


Answer: C. Nystatin

18. The drug that increases blood flow to the splanchnic areas as well as the kidney and increases glomerular filtration rate thus leading to sodium diuresis along with an increase in cardiac output?
A. Dopamine
B. Epinephrine
C. Norepinephrine
D. Isoproterenol

Answer: A. Dopamine

19. Which of the following drugs were eliminated unchanged in the urine?
A. Oseltamivir
B. Zanamivir
C. Zidovudine   
D. A & B  
E.  All of the above 


Answer: D. A & B

20. Which one of the following drugs is only available as an ophthalmic ointment and used to treat vaccinial keratitis?
A. Penciclovir
B. Gancyclovir 
C. Foscarnet 
D. Vidarabine 
E. Fomivirsen 


Answer: D. Vidarabine 

21. Which of the following was the only efficacious antifungal drug available for systemic use?
A. Amphotericin B
B. posaconazole
C. caspofungin
D. Nystatin


Answer: A. Amphotericin B

22. Which one of the following drugs has high oral bioavailability than others?
A. Gancyclovir
B. Valganciclovir
C. Penciclovir
D. Fomivirsen 
E. Vidarabine


Answer: B. Valganciclovir


23. Autoimmune diseases such as goodpasture's syndrome (caused by antibodies to the basement membrane of the kidney) myasthenia gravis is example of?

A. Type I hypersensitivity 
B. Type II hypersensitivity 
C. Type III hypersensitivity 
D. Type IV hypersensitivity 

Answer: Type II hypersensitivity reactions also called cytotoxic or antibody dependent hypersensitivity.
Other examples: infusion related reactions, 
New born hemolytic disease where maternal antibodies destroy the fatal RBCs because of incompatible blood type

24. Hypersensitivity reactions involves antibody dependent reactions to soluble antigens by forming immune complex between antibody and soluble antigen?
A. Type I hypersensitivity 
B. Type II hypersensitivity 
C. Type III hypersensitivity 
D. Type IV hypersensitivity 

Answer: Type III hypersensitivity 
Examplea: Serum sickness (injection of foreign antigen leading to formation and deposition of immune complex in blood vessels, Arthus Reactions ( subcutaneous immune complex formation occurring at a local site in and around the wall of small blood vessels), Systemic lupus erythematosus (caused by antibodies to DNA, histone, and antigens of the nucleus)

1 comment:

  1. Hats off to the moderator .. very useful review of the mcqs

    ReplyDelete