01. Which one of the following drugs is a Meglitinide drug?
A. Hydrochlorothiazide
B. Nateglinide
C. Fenofibrate
D. Ezetimibe
E. Indanyl carbenicillin
Answer: B. Nateglinide
02. Which of the following drug belongs to Sulfonylureas?
A. Niacin
B. Cefoxitin
C. Tolbutamide
D. Urae
E. Oxacillin
Answer: C. Tolbutamide
03. Which one of the following drugs is first generation flouroquinolone?
A. Ciprofloxacin
B. Levofloxacin
C. Nalidixic acid
D. Moxifloxacin
Answer: C. Nalidixic acid
04. A drug that belongs to thiazolidinediones is one of the following?
A. Pioglitazone
B. Ethacrynic Acid
C. Cefazolin
D. Sulbactam
E. A & B
Answer: A. Pioglitazone
A. Hydrochlorothiazide
B. Nateglinide
C. Fenofibrate
D. Ezetimibe
E. Indanyl carbenicillin
Answer: B. Nateglinide
02. Which of the following drug belongs to Sulfonylureas?
A. Niacin
B. Cefoxitin
C. Tolbutamide
D. Urae
E. Oxacillin
Answer: C. Tolbutamide
03. Which one of the following drugs is first generation flouroquinolone?
A. Ciprofloxacin
B. Levofloxacin
C. Nalidixic acid
D. Moxifloxacin
Answer: C. Nalidixic acid
04. A drug that belongs to thiazolidinediones is one of the following?
A. Pioglitazone
B. Ethacrynic Acid
C. Cefazolin
D. Sulbactam
E. A & B
Answer: A. Pioglitazone
05. Which one of the following drugs is 2nd generation flouroquinolone?
A. Ciprofloxacin
B. Levofloxacin
C. Nalidixic acid
D. Moxifloxacin
Answer: A. Ciprofloxacin
06. A disease in which blood vessels become inflamed and this inflammation leads to restriction of blood flow to organs and tissues also sometimes permanently damage organs is called?
A. Steven-johnson syndrome
B. Ductus arteriosus
C. Churg Strauss syndrome
D. Reye syndrome
E. Hypotrichosis
Answer: C. Churg Strauss syndrome
A. Ciprofloxacin
B. Levofloxacin
C. Nalidixic acid
D. Moxifloxacin
Answer: A. Ciprofloxacin
06. A disease in which blood vessels become inflamed and this inflammation leads to restriction of blood flow to organs and tissues also sometimes permanently damage organs is called?
A. Steven-johnson syndrome
B. Ductus arteriosus
C. Churg Strauss syndrome
D. Reye syndrome
E. Hypotrichosis
Answer: C. Churg Strauss syndrome
07. Which of the following drug can disrupt the enteric coating by increasing the Gastric PH?
A. Sitagliptin
B. Cefoxitin
C. Glimepiride
D. Omeprazole
E. Oxacillin
Answer: D. Omeprazole
Because when Omeprazole increase the gastric PH towards neutral. when PH of gastric acid increased this results in providing the enteric coated tablets a favourable environment to release drug.
08. Which one of the following is the adverse effect of ACE inhibitors?
A. Dry cough
B. Skin rashes
C. hypokalaemia
D. A & B
E. All of the above
Answer: D. A & B
09. A drugs interfere with metabolism of azathioprine requiring a reduction in dosage?
A. Probenecid
B. Sulfinpyrazone
C. Colchicine
D. Allopurinol
Answer: D. Allopurinol
10. Aldosterone production is reduced by using one of the following drugs?
A. Lisinopril
B. Aspirin
C. Erythromycin
D. Diltiazem
Answer: A. Lisinopril
A. Sitagliptin
B. Cefoxitin
C. Glimepiride
D. Omeprazole
E. Oxacillin
Answer: D. Omeprazole
Because when Omeprazole increase the gastric PH towards neutral. when PH of gastric acid increased this results in providing the enteric coated tablets a favourable environment to release drug.
08. Which one of the following is the adverse effect of ACE inhibitors?
A. Dry cough
B. Skin rashes
C. hypokalaemia
D. A & B
E. All of the above
Answer: D. A & B
09. A drugs interfere with metabolism of azathioprine requiring a reduction in dosage?
A. Probenecid
B. Sulfinpyrazone
C. Colchicine
D. Allopurinol
Answer: D. Allopurinol
10. Aldosterone production is reduced by using one of the following drugs?
A. Lisinopril
B. Aspirin
C. Erythromycin
D. Diltiazem
Answer: A. Lisinopril
11. Following disease is inherited disorder of copper metabolism characterized by reduced serum copper & increased cincentration of copper in brain & viscera
A. parkinsons disorder
B. wilsons disorder
C. restless legs syndrome
D. Gout
A. parkinsons disorder
B. wilsons disorder
C. restless legs syndrome
D. Gout
Answer: B. wilsons disorder
12. Surgical removal of Fallopian tubes is called?
A. Salpingdectomy
B. Ostectomy
C. Posthectomy
D. Rhinectomy
E. Orchiectomy
Answer: A. Salpingdectomy
A. Salpingdectomy
B. Ostectomy
C. Posthectomy
D. Rhinectomy
E. Orchiectomy
Answer: A. Salpingdectomy
13. Which one of the following drugs is an inhibitor of folate synthesis?
A. Sulfasalazine
B. Erythromycin
C. Clarithromycin
D. Levofloxacin
Answer: A. Sulfasalazine
A. Sulfasalazine
B. Erythromycin
C. Clarithromycin
D. Levofloxacin
Answer: A. Sulfasalazine
14. Which of the following drugs bind to the 50S subunit causing inhibition of translocation?
A. Erythromycin
B. Clindamycin
C. Streptomycin
D. A & B
E. All of the above
Answer: D. A & B
A. Erythromycin
B. Clindamycin
C. Streptomycin
D. A & B
E. All of the above
Answer: D. A & B
15. Salicylates Potentiate the effects of following drugs as a drug interaction?
A. Anticoagulants
B. Thrombolytic agents
C. PPIs
D. A & B
E. All of the above
Answer: D. A & B
16. Which one of the following neurotransmitters mediates the Na+ influx into the postsynaptic neuron and works as excitatory?
A. Substance P
B. Met-enkephalins
C. Glutamate
D. GABA
E. Serotonin
A. Substance P
B. Met-enkephalins
C. Glutamate
D. GABA
E. Serotonin
Answer: C. Glutamate
17. Which one of the following symptoms is linked with the overdose of the Ganglion blocker drug?
A. Increased blood pressure
B. Miosis
C. Tachycardia
D. Increased Sweating
E. Increased bowel movement
Answer: C. Tachycardia
Because the pupil and the sinoatrial node are dominated by the Parasympathetic system when the sympathetic and Parasympathetic systems are blocked by ganglion blocker drugs. leading to tachycardia and Mydriasis.
18. A 40-year-old female is on 6-mercaptopurine for treatment of acute lymphocytic leukemia. Which of the following drugs may not be used to reduce the resultant uric acid levels?
A. Allopurinol
B. Colchicine
C. Indomethacin
D. Probenecid
E. Sulindac
Answer: A. Allopurinol
19. Which one of the following types of hepatitis is not a chronic disease and commonly encountered infection?
A. Hepatitis A
B. Hepatitis B
C. Hepatitis C
D. A & B
E. B & C
Answer: A. Hepatitis A
A. Hepatitis A
B. Hepatitis B
C. Hepatitis C
D. A & B
E. B & C
Answer: A. Hepatitis A
20. When the level of prostacyclin is decreased then the binding of prostacyclin to platelet receptor is also decreased resulting in?
A. Increase level of intracellular cAMP
B. Lower level of intracellular cAMP
C. Increase level of Ca++
D. Decrease level of Ca++
E. Both B & C
Answer: E. Both B & C
A. Increase level of intracellular cAMP
B. Lower level of intracellular cAMP
C. Increase level of Ca++
D. Decrease level of Ca++
E. Both B & C
Answer: E. Both B & C
21. Sympathetic nervous system has a following type of response?
A. Diffuse
B. Discrete
C. Minimal
D. Extensive
Answer: A. Diffuse
22. ParaSympathetic nervous system has a following type of response?
A. Diffuse
B. Discrete
C. Minimal
D. Extensive
Answer: B. Discrete
23. Following drugs is cleared by organ independent metabolism (Hofmann elimination)?
A. Cisatracurium
B. Pancuronium
C. Vecuronium
D. Rocuronium
Answer: Cisatracuronium
Pancuronium is renally eliminated and can't be used in renal failure patients.
Vecuronium and rocuronium are hepatically metabolized and can't be used in liver disease patients.
24. Systemic lupus erythematosus (caused by antibodies to DNA, histone, and antigens of the nucleus) is an example of?
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity
D. Type IV hypersensitivity
Answer: Type III hypersensitivity
Examplea: Hypersensitivity reactions involves antibody dependent reactions to soluble antigens by forming immune complex between antibody and soluble antigen,
Arthus Reactions ( subcutaneous immune complex formation occurring at a local site in and around the wall of small blood vessels
25. Tuberculina reaction (local reaction of inflammation and redness at the site of subcutaneous injection of prepared antigen
From Mycobacterium tuberculosis Is following type?
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity
D. Type IV hypersensitivity
Answer: D. Type IV hypersensitivity also called delayed type hypersensitivity DTH Type of hypersensitivity mediated by a memory T-cell response that have been sensitised to an allergin by a previous contact recruit other leukocytes to the site of allergin upon a later encounter
Because of the recruitment a delay occurs in the allergic reaction.
Example:
Contact dermatitis allergen contact with the epidermis resulting in inflammation and redness caused by infiltration of leukocytes and cytokine release
Granulomatous reaction Stimulation from a foreign body or particulate such as talc or silica resulting in a granuloma, which is a mass of lymphocytes and macrophages surrounding an allergen too large to be phagocytized.
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