PHARMACOLOGY QUIZZES 61 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs belongs to 1st generation Cephalosporins?
A. Cefaclor
B. Cefadroxil
C. Cefdinir
D. Cefepime

Answer: B. Cefadroxil

02. Which one of the following drugs is a 2nd generation Cephalosporin?
A. Cefaclor
B. Cefadroxil
C. Cefdinir
D. Cefepime

Answer: A. Cefaclor 

03. Every 4 to 6 hours dose of Ibuprofen for adults should be administered as needed is following?
A. 160 mg
B. 200 to 400 mg
C. 325 to 650 mg
D. 650 to 1000 mg
E.  1600 mg

Answer: B. 200 to 400 mg

04. Every 8 to 12 hours dose of Naproxen for adults should be administered as needed if the maximum daily dose is 660 mg is following?
A. 160 mg
B. 220 mg
C. 325 to 650 mg
D. 650 to 1000 mg
E. 1600 mg

Answer: B. 220 mg

05. A drug that is more effective in combination with itraconazole to treat chromoblastomycosis?
A. Nystatin
B. Griseofulvin
C. Amphotericin B
D. Flucytosine

Answer: D. Flucytosine

06. Which of the following statements about Virus is incorrect?

A. Antiviral effects Viral replication 

B. Lack independent metabolic activity 

C. Can replicate only within host cell

D. Antiviral drugs injure host cell too

E. None of these 

Answer: E. None of these 

07. Which of the following statements about Bile acid sequestrants is wrong?

A. Hydrophilic 

B. Insoluble anion exchange resins 

C. Form slurry and gel formation after ingestion 

D. These drugs are negatively charged 

E. Cholestyramine, Colesevelam, Colestipol

Answer: D. These drugs are negatively charged 

Infact these drugs has positive charge and they bind with negatively charged bile acid to stop the reabsorption of bile acid.

08. A drug consists of trimethylbenzylammonnium groups in a large copolymer of styrene and divinylbenzene?

A. Cholestyramine 

B. Colestipol

C. Colesevelam

D. A & B

E. All of the above 

Answer: A. Cholestyramine 

09. A drug consists copolymer of diethylenetriamine and 1-chloro-2,3-epoxypropane in a hygroscopic powder?

A. Cholestyramine 

B. Colestipol

C. Colesevelam

D. A & B

E. All of the above 

Answer: B. Colestipol 

 

10. A drug that polyallylamine cross linked with epichlorohydrin and alkylated with 1-bromodecane and trimethylammonium bromide in a hydrophilic gel?

A. Cholestyramine 

B. Colestipol

C. Colesevelam

D. A & B

E. All of the above 

Answer: C. Colesevelam

11. Following drugs are positively charged but one of them becomes positively charged in the small intestine?

A. Cholestyramine 

B. Colestipol

C. Colesevelam

D. A & B

E. All of the above 

Answer: B. Colestipol 

Cholestyramine and colesevelam are positively charged drugs but Colestipol becomes positive in small intestine to bind with negatively charged bile acid. 

12. Following drugs reduce circulating LDL levels by 10% to 25% ?

A. Bile acid sequesterants

B. HMG-CoA reductase inhibitors

C. Mevalonate

D. A & B

E. None of these 

Answer: A. Bile acid sequestrants

These drugs reduce 10-25% circulating LDL levels but HMG-CoA reductase inhibitors reduce LDL levels upto 60% .

While mevalonate is product during  synthesis of cholesterol.

13. Which of the following statements about bile acid sequestrants is wrong?

A. Reduce LDL levels by 10-25%

B. Gastric distress, bloating, flatulence are ADRs

C. Increase absorption of Warfarin and statins 

D. Hydrophilic in nature 

E. Stop absorption of bile acid 

Answer: C. Increase absorption of warfarin and statins 

Infact they decrease absorption of these drugs.

14. Hyperchylomicronemia is treated by following therapy?

A. Omega-3 fatty acid 

B. Cholestyramine 

C. Simvastatin

D. Gemfibrozil

E. low fat diet 

Answer: E. low fat diet 

This type is treated with low fat diet only no drugs therapy is effective for this disease.

15. Which of the following nonstatin drugs lowers LDL-C most effectively?

A. Ezitimibe

B. Cholestyramine 

C. Niacin 

D. Alirocumab

Answer: D. Alirocumab

16. Which of the following drugs is Proprotein convertase subtilisin kexin type 9 inhibitors?

A. Ezitimibe

B. Cholestyramine 

C. Niacin 

D. Alirocumab

Answer: D. Alirocumab

This drug can lower LDL-C upto 70% in patients on statin therapy.

17. Which of the following drugs raises HDL-C and decrease triglycerides with less potent effects on LDL-C?

A. Ezitimibe

B. Cholestyramine 

C. Niacin 

D. Alirocumab

Answer: C. Niacin 

18. Which of the following drugs is more potently lower LDL-C from circulation?

A. Ezitimibe

B. Cholestyramine 

C. Niacin 

D. Alirocumab

Answer: D. Alirocumab

19. A 65 years old man has type 2 diabetes mellitus and an LDL-C of 165 mg/dL. Which is the best option to lower LDL-C and decrease the risk of ASCVD events in this patient?

A. Colesevelam

B. Fenofibrate

C. Rosuvastatin 

D. Ezitimibe

Answer: C. Rosuvastatin

ASCVD: atherosclerotic cardiovascular disease 

Rosuvastatin is a statin that inhibit the HMG-CoA reductase and is the most effective in reducing LDL-C upto 60% from baseline levels. 

20. Which of the following drug is most effective option to lower LDL-C levels?

A. Ezitimibe 

B. Rosuvastatin 

C. Fenofibrate

D. Colesevelam

Answer: B. Rosuvastatin 

All others drugs are less effective to lower levels as compared to statins.

21. Parasympathetic preganglionic fibers arise from sacral region S2 to S4 as well as cranial nerve III, VII, IX and X. Cranial nerve III called?

A. Oculomotor

B. Facial 

C. Glossopharyngeal

D. Vagus

Answer: A. Oculomotor