PHARMACOLOGY QUIZZES 57 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is a Alpha Glucosidase inhibitors?
A. Hydrochlorothiazide  
B. Repaglinide  
C. Acarbose
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: C. Acarbose 

02. Amantadine belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: A. Antiviral 

03. Which of the following drug belongs to Sulfonylureas?
A. Niacin
B. Cefoxitin 
C. Glyburide 
D. Urae
E. Oxacillin

Answer: C. Glyburide 

04. A direct-acting adrenergic agonist is following?
A. Clonidine
B. Albuterol
C. Amphetamine
D. Acetylcholine
E. A & B

Answer: E. A & B

03. A drug that belongs to DPP-IV inhibitors  is one of the following?
A. Rosiglitazone 
B. Ethacrynic Acid
C. Sitagliptin
D. Sulbactam
E. A & B

Answer: C. Sitagliptin 

04. Cardiac glycosides are used in the treatment of congestive heart failure and atrial fibrillation. Given the differences between the cardiac glycosides in their length of action and organs of major excretion, the correct statement concerning the use of digitoxin is:
A. gastrointestinal absorption of digitoxin is incomplete and highly variable within patients
B. digitoxin is excreted primarily unchanged in the kidney with a half-life of about 24 hours
C. digitoxin is highly protein-bound in the serum
D. digitoxin has a much higher incidence of toxicity in patients with renal disease
E. digitoxin is only available as an oral preparation

Answer: C. digitoxin is highly protein-bound in the serum

05. Verapamil, a calcium channel antagonist:

a. Increases intracellular cAMP

b. Decreases myocardial contractility

c. Increases reactivation of sodium channels

d. Decreases intracellular K

e. Increases conduction velocity

Answer: Decreases myocardial contractility

06. The cough associated with Captopril is most likely associated with?
a. Decrease in the metabolism of acetylcholine
b. Direct airway irritation
c. Increase in bradykinin levels
d. Release of histamine
e. Stimulation of adenosine receptors in the lungs 

Answer: Increase in bradykinin levels

07. A 69-year-old male with angina develops severe constipation following treatment with:
a. Propranolol 
b. Captopril
c. Verapamil
d. Dobutamine 
e. Nitroglycerin

Answer: Verapamil

08. Which one of the following statements about the functions of ACE inhibitors is wrong?
A. Decrease output of the sympathetic nervous system
B. Increase vasodilation of vascular smooth muscle
C. Increase retention of sodium and water
D. Increase level of bradykinin

Answer: C. Increase retention of sodium and water

09. A drug is more effective when combined with Flucytosine to treat candidiasis or cryptococcosis?
A. Itraconazole
B. Amphotericin B
C. Caspofungin
D. Griseofulvin


Answer: B. Amphotericin B

10. Which one of the following drugs induce Dose Dumping syndrome?
A. Erythromycin 
B. Digoxin 
C. Amiodarone 
D. Rifampin 
E. Ethanol  

Answer: E. Ethanol  

11. Aspirin is contraindicated in following disease?
A. Peptic ulcer 
B. Bleeding disorder 
C. Reye's syndrome 
D. A & B
E. All of these 

Answer: E. All of these 

12. Which of the following is most likely to occur with carbonic anhydrase inhibitors?
A. Hyperkalemia 
B. Alkalosis
C. Acidic urine
D. Hyperchloremia
E. Hyperuricemia 

Answer:D.  Hyperchloremia

13. Drugs that show capacity-limited elimination have which of the following property?
A. A constant ratio of drug metabolites are formed as the administered dose increases
B.First-order elimination kinetics is followed by low and high doses both
C. The elimination half-life(t½) remains constant
D. As the administered dose increases the elimination half-life (t½) increases 

Answer: D. As the administered dose increases the elimination half-life (t½) increases 

14. Which one of the following interferon drugs have been approved for the treatment of Kaposi's sarcoma?
A. Interferon-alpha
B. Interferon-Beta
C. Interferon-Gamma
D. A & B
E. All of these 

Answer: Interferon-alpha 

15. Which disease is associated with rigidity, bradykinesia, tremors, &  postural instability
A. meningitis
B. parkinsonism
C. Addison's disease
D. malaria 

Answer: B. Parkinsonism

16. Cyclooxygenase enzyme is responsible for the production of the following?

A. Prostaglandins 
B. Thromboxane
C. Arachidonic Acid
D. A & B
E. All of the above 

Answer: D. A & B

17. A drug that concentrates on the endolymph of the ear causing dizziness, nausea, and vomiting?
A. Glyburide
B. Tolbutamide
C. Sitagliptin
D. Minocycline 

Answer: D. Minocycline

18. Which one of the following drugs is guanosine analog?
A. Cidofovir
B. Foscarnet 
C. Fomivirsen 
D. Acyclovir 
E. Trifluridine

Answer: D. Acyclovir

19. Parasympathetic preganglionic fibers arise from sacral region S2 to S4 as well as cranial nerve III, VII, IX and X. Cranial nerve X called?

A. Oculomotor

B. Facial 

C. Glossopharyngeal

D. Vagus

Answer:  D. Vagus

A. Oculomotor III

B. Facial VII

C. Glossopharyngeal IX

D. Vagus X

20. Which one of the following drugs is preferred for those patients with gastric complaints?
A. Acetaminophen 
B. Diflunisal 
C. Aspirin 
D. A & B
E. All of the above 

Answer: A. Acetaminophen 

21. Orthostatic hypotension is associated with one of the following drugs?
A. Labetalol
B. Timolol
C. Nadolol
D. Pindolol
E. Metoprolol

Answer: A. Labetalol due to Alpha-1 blockage

22. A drug causes inhibition of nucleotides reverse transcriptase?
A. Rimantadine 
B. Vidarabine 
C. Zanamavir 
D. Acyclovir 
E. Lamivudine 

Answer: E. Lamivudine