Controlled Drugs MCQs. 62

01. Which one of the following drugs is not active orally and is either inhaled or administered intranasally?
A. Oseltamivir
B. Adamantadine
C. Zanamivir 
D. Amantadine
E. None of these 

Answer: C. Zanamivir 

02. A 36 years old lady is taking imipramine for phobic anxiety disorder and her 25 years old husband is being treated with chlorpromazine for a psychotic disorder. Which of the following adverse effects is likely to occur in both of these individuals?
A. Decreased seizure threshold
B. Excessive salivation
C. Orthostatic hypotension
D. Pupillary constriction
E. Weight loss

Answer: C. Orthostatic hypotension.

03. Which one of the following drugs is long Acting benzodiazepines?

A. Temazepam 
B. Triazolam 
C. Zolpidem 
D. Flurazepam 

Answer: D. Flurazepam

Classification of Benzodiazepines:

Short Acting: Triazolam, Oxazepam, Midazolam 

Intermediate: Alprazolam, Temazepam, Estazolam, Lorazepam 

Long Acting: Diazepam, Flurazepam, Chlordiazepoxide, Quazepam, Clorazepate, Clonazepam

04. Which one of the following drugs is an intermediate-acting benzodiazepine?
A. Zaleplon 
B. Flurazepam
C. Temazepam
D. Triazolam

Answer: Temazepam

05. Which one of the following drugs is a short-acting benzodiazepine?
A. Eszopiclone 
B. Flurazepam
C. Triazolam
D. Temazepam

Answer: C. Triazolam

06. Which one of the following drugs is a nonbenzodiazepine drug?
A. Triazolam
B. Flurazepam
C. Zolpidem
D. Temazepam


Answer: C. Zolpidem

07. Alprazolam belongs to one of the following classes of benzodiazepines?
A. Short Acting benzodiazepine
B. Long Acting benzodiazepines
C. Intermediate Acting benzodiazepine
D. Nonbenzodiazepine


Answer: C. Intermediate Acting benzodiazepine 

 
08. Clonazepam belongs to one of the following classes of benzodiazepines?
A. Short Acting benzodiazepine
B. Intermediate Acting benzodiazepine
C. Long Acting benzodiazepines
D. Nonbenzodiazepine


Answer: C. Long-Acting benzodiazepines


09. Which one of the following actions of benzodiazepines is true?
A. Muscle relaxant
B. Anticonvulsant
C. Anterograde amnesia
D. A & B 
E. All of the above

Answer: E. All of the above


10. Which one of the following drugs is a less potent and more slowly eliminated drug?
A. Triazolam
B. Alprazolam
C. Temazepam
D. Flurazepam 

Answer: D. Flurazepam

11. Which one of the following drugs is an antagonist to benzodiazepines?
A. Buspirone 
B. Hydroxyzine
C. Flumazenil
D. Zolpidem

Answer: C. Flumazenil 


12. Which of the following drugs are hypnotic agents? 
A. Phenobarbital
B. Antihistamine
C. Zolpidem
D. Chloral hydrate 
E. All of the above

Answer: E. All of the above


13. Which one of the following statements about the actions of benzodiazepines is wrong?
A. Reduce anxiety
B. Causes Sedation 
C. Memory impairment
D. Analgesic activity

Answer: D. Analgesic activity

14. A Benzodiazepine that continues to improve sleep even after discontinuation?
A. Triazolam
B. Alprazolam
C. Flurazepam
D. Temazepam 

Answer: C. Flurazepam

15. Which one of the following anxiolytic drugs causes hypothermia and increases prolactin and growth hormone?
A. Buspirone
B. Hydroxyzine
C. Venlafaxine 
D. Triazolam

Answer: A. Buspirone


16. Which one of the following barbiturate drugs has long Acting activity?
A. Pentobarbital
B. Thiopental
C. Phenobarbital
D. Buspirone

Answer: A. Phenobarbital 


17. A Benzodiazepine drug that is more potent and rapidly eliminate from the body?
A. Alprazolam
B. Triazolam
C. Temazepam 
D. Flurazepam

Answer: B. Triazolam

18. Which one of the following drugs has more frequent and severe withdrawal problems with rapidly eliminating property?
A. Alprazolam
B. Diazepam
C. Triazolam
D. Flurazepam

Answer: C. Triazolam

19. Neostigmine will effectively antagonize skeletal muscle relaxation produced by
a) Baclofen
b) Diazepam
c) Nicotine
d) Pancuronium

Answer: d) Pancuronium 

Because Neostigmine is a competitive neuromuscular blocking agent used to manage myasthenia gravis with a duration of 30 minutes to 2 hours.

Duration of Action of indirect acting cholinergic agonist or anticholinesterases agents (Reversible)

Edrophonium: 10 to 20 minutes 

Physostigmine (natural): 30 minutes to 2 hours 

Neostigmine (synthetic): 30 minutes to 2 hours 

Pyridostigmine: 3 to 6 hours longer than Neostigmine 

20. Applied to the skin in a transdermal patch (transdermal therapeutic delivery system), this drug is used to prevent or reduce the occurrence of nausea and vomiting that are associated with motion sickness
A. Chlorpromazine
B. Dimenhydrinate
C. Diphenhydramine
D. Ondansetron
E. Scopolamine


Answer: E. Scopolamine

21. Toxicity of following drugs can cause stunted growth in adolescent shrinkage of testicles, gynecomastia, increased risk of prostate cancer in men?

A. Androgenic anabolic steroids 

B. Barbiturates 

C. Cocaine

D. Dextromethorphan 

E. Ethanol 

Answer: A. Androgenic anabolic steroids 

These steroids are taken by orally or injected in cycles of weeks or months.