Controlled Drugs MCQs 63

01. Drowsiness and confusion is the adverse effect of one of the following drugs?
A. Flumazenil
B. Tetracyclin
C. Candesartan 
D. Alprazolam

Answer: Alprazolam
Benzodiazepines have these two adverse effects commonly.

02. Which one of the following drugs is a short Acting barbiturate drug?
A. Thiopental
B. Secobarbital
C. Phenobarbital
D. Hydroxyzine

Answer: B. Secobarbital

03. Which one of the following drugs is used to reduce the toxicity of Diazepam?
A. Pyridostigmine
B. Pyridoxine
C. Flumazenil
D. Cyproheptadine
E. A & B 

Answer: C. Flumazenil

04. Flumazenil is used to reduce the toxicity of one of the following drugs?
A. Pyridostigmine
B. Lead 
C. Fluoxetine
D. Triazolam

Answer: D. Triazolam

05. A drug that blocks the 5-HT³ serotonin receptor is one of the following drugs?
A. Ondansetron
B. Pyridoxine
C. Scopolamine
D. Metoclopramide


Answer: A. Ondansetron

06. Ritodrine hydrochloride is used in the treatment of
a) Bronchial asthma
b) Depression
c) Hypertension
d) Parkinson’s disease
e) Premature labor 

Answer: e) Premature labor 

07. The reversible cholinesterase inhibitor indicated in the treatment of Alzheimer's disease is
a) Ambenonium
b) Edrophonium
c) Neostigmine
d) Pyridostigmine
e) Tacrine


Answer: e) Tacrine

08. What is the antidote to protriptyline?
A. Coumadin
B. Labetalol
C. Diazepam
D. Sodium Bicarbonate

Answer: D. Sodium Bicarbonate
Sodium Bicarbonate is used to maintain alkalinization. An arterial PH of 7.45 to 7.55 decreases the free fraction of absorbed toxins.

09. What is the antidote of Triazolam?
A. Heparin
B. Pyridostigmine
C. Atropine
D. Flumazenil


Answer: D. Flumazenil

10. Which one of the following drugs is a potent inhibitor of alcohol dehydrogenase thus preventing the formation of toxins by ethylene glycol or methanol?
A. Pyridostigmine
B. Coumarin 
C. Deferoxamine
D. Fomepizole



Answer: D. Fomepizole

11. Which one of the following antidepressants has a narrow therapeutic index?
A. Doxepin
B. Citalopram
C. Trazodone
D. Sertraline


Answer: A. Doxepin


12. An antidepressant drug that has a wide therapeutic index is one of the following drugs?
A. Paroxetine
B. Protriptyline
C. Desipramine
D. Amitriptyline


Answer: A. Paroxetine


13. Phenelzine belongs to one of the following classes of antidepressants?
A. MAOIs
B. SNRIs
C. SSRIs
D. Tricyclics


Answer: A. MAOIs

14. Peripheral effects are the adverse effect of Levodopa, this adverse effect is diminished by adding one of the following drugs in the therapy?
A. Amantadine
B. Carbidopa
C. Selegiline
D. Ropinirole
E. Entacapone

Answer: B. Carbidopa


15. Which one of the following drugs belongs to the serotonin/norepinephrine/dopamine reuptake inhibitor (SNRIs)?
A. Venlafaxine
B. Fluoxetine
C. Nortriptyline
D. Trazodone


Answer: A. Venlafaxine

16. Paroxetine is an antidepressant drug that belongs to one of the following types?
A. SNRIs
B. SSRIs
C. Tricyclics
D. MAOIs


Answer: B. SSRIs

17. Which one of the following drugs is an antidepressant Acting as a noradrenaline-specific reuptake inhibitor (NRI)?
A. Phenelzine
B. Reboxetine
C. Paroxetine
D. Citalopram


Answer: B. Reboxetine

18. When one of the following drugs is administered later than mid-afternoon it produces insomnia?
A. Amantadine
B. Carbidopa
C. Selegiline
D. Ropinirole
E. Entacapone


Answer: C. Selegiline
Because selegiline is metabolized to amphetamine and methamphetamine, these are CNS stimulating drugs thus causing insomnia.

19. One of the following drugs is COMT inhibitor?
A. Entacapone
B. Levodopa
C. Amantadine
D. Ropinirole
E. Selegiline

Answer: A. Entacapone 
Entacapone
It's a COMT inhibitor drug used in Parkinson's disease to enhance the concentration of Levodopa in the CNS. it acts by decreasing the plasma concentration of 3-O-methyldopa that competes with Levodopa for active transport into the CNS.


20. Which one of the following drugs is a selectively MAO type B inhibitor drug?
A. Entacapone
B. Levodopa
C. Amantadine
D. Ropinirole
E. Selegiline 

Answer: E. Selegiline