MEDICOLOGY: APHA FPGEE exam practice MCQs No. 79

Tuesday, August 2, 2022

APHA FPGEE exam practice MCQs No. 79

01. Chromosomes become highly condensed in following phase?
A. Prophase 
B. Metaphase
C. Anaphase 
D. Telophase 

Answer: A. Prophase 

02. Chromosomes have achieved their highest state of condensation. They are attached to the spindle fiber and
aligned at the metaphase (equatorial) plate. During this phase, chromosomes are amenable to microscopic
analysis?
A. Prophase 
B. Metaphase
C. Anaphase 
D. Telophase 

Answer: B. metaphase

03. The centromere of each chromosome divides, and the two daughter chromosomes segregate along the spindle
fibers toward the centrioles, located at each pole?
A. Prophase 
B. Metaphase
C. Anaphase 
D. Telophase 

C. Anaphase 

04. Two new nuclear membranes form, and the cytoplasm is divided in half by cytokinesis. Two identical daughter
cells are the products of mitosis?
A. Prophase 
B. Metaphase
C. Anaphase 
D. Telophase 

Answer: D. TeloPhase

21. Preeclampsia (hypertension, proteinurea, edema) should be treated as follows?
A. IV hydralazine or labetalol
B. IV magnesium sulfate 
C. Ace inhibitors 
D. A & B
E. All of the above  

Answer: D. A & B

22. DOC in Venous thromboembolism in pregnant women?
A. Heparin 
B. Warfarin 
C. Lisinopril
D. Acetazolamide

Answer: A. Heparin (LMW heparin are alternate choice)
Warfarin should be avoided after 6 weeks of pregnancy bcoz it causes fetal bleeding, malformation or central nervous system anomalies.

23. When following drug used to treat headaches in pregnancy it causes bleeding and closure of ductus arteriosus?
A. Acetaminophen 
B. Aspirin 
C. Heparin 
D. Warfarin 

Answer: B. Aspirin 
Acetaminophen is DOC in headaches in pregnancy.

24. A drug causes increased risk of kernicterus to the neonates when used in third trimester of pregnancy?
A. Ampicillin 
B. Amoxicillin 
C. Sulfa drugs
D. Nitrofurantoin
E. Cephalexin

Answer: C. Sulfa drugs 

25. A drug should be avoided in pregnancy causing folate reduction?
A. Ampicillin 
B. Amoxicillin 
C. Sulfa drugs
D. Nitrofurantoin
E. Trimethoprim 

Answer: E. Trimethoprim (folate antagonist)

26. Following drugs are safe to use in pregnancy except?
 A. Ampicillin 
B. Amoxicillin 
C. Cephalexin
D. Nitrofurantoin
E. Trimethoprim 

Answer: E. Trimethoprim 
Ampicillin and Amoxicillin are safe in pregnancy for escherichia coli but now they show increasing resistance against E. coli. 
Fluoroquinolones and tetracycline are contraindicated in pregnancy.
Syphilis transmitted trans placentally and must be treated early in sexually transmitted diseases (STD)

27. Safe drugs used for allergic rhinitis and asthma during pregnancy?
A. Chlorpheniramine
B. Beclomethasone
C. Beta2 agonist 
D. Theophylline 
E. All of these 

Answer: E. All of these 
Chlorpheniramine as oral antihistamine and orally inhaled corticosteroids are recommended.
Beta2 agonist for bronchodilation and theophylline is second option.
A nasal decongestant pseudoephedrine and Prednisone as a burst in acute exacerbation.
Dermatology: Avoid retinoid compounds 

28. Following is the recommended drug in HIV after the 14th week of gestation for the duration of pregnancy?
A. Ampicillin 
B. Amoxicillin 
C. Cephalexin
D. Zidovudine
E. Trimethoprim 

Answer: D. Zidovudine 

29. One of the Following drugs preferred in pregnancy used to treat hyperthyroidism?
A. Levothyroxine
B. Propylthiouracil
C. Methimazole
D. Carbamazepine 
E. Valproate 

Answer: B. Propylthiouracil
Levothyroxine is used to treat hypothyroidism not hyperthyroidism.
Propylthiouracil is preferred than methimazole because it cross placenta less readily than methimazole.
Carbamazepine and Valproate are used in pregnancy but causes congenital malformation.

30. An autosomal recessive disease involves a defect in chloride transport channel resulting in decreased function of exocrine glands leading to GI and pulmonary disturbance?
A. Hyperthyroidism 
B. Cystic fibrosis 
C. Ciliac disease 
D. Maple syrup urine disease 
E. Sickle cell anemia 

Answer: B. Cystic fibrosis 
GI problem increased viscosity  of  mucus secretion, deficiency of pancreatic digestive enzymes and decreased bicarbonate secretion.
Enzymes deficiency causes poor digestion, fat soluble vitamin deficiency 

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