01. Following is the basic structure of following component?
A. Amino Acid
B. Protein
C. Lipids
D. Carbohydrates
E. Glucose
Answer: A. Amino Acid basic structure
02. Following formula structure belongs to following non essential Amino acid?
A. Arginine
B. Asparagine
C. Aspartic Acid
D. Alanine
E. Cysteine
Answer: A. Arginine (Arg/R)
03. Following formula structure belongs to following Amino acid?
A. Arginine
B. Asparagine
C. Aspartic Acid
D. Alanine
E. Cysteine
Answer: B. Asparagine (Asn/N)
04. Following formula structure belongs to following Amino acid?
A. Arginine
B. Asparagine
C. Aspartic Acid (Aspartate)
D. Alanine
E. Cysteine
Answer: C. Aspartic Acid (Aspartate) (Asp/D)
05. Following formula structure belongs to following Amino acid?
A. Arginine
B. Asparagine
C. Aspartic Acid (Aspartate)
D. Alanine
E. Cysteine
Answer: E. Cysteine (Cys/C)
06. Following formula structure belongs to following Amino acid?
A. Arginine
B. Asparagine
C. Aspartic Acid (Aspartate)
D. Alanine
E. Cysteine
Answer: D. Alanine (Ala/A)
07. Following is the structure formula of one of the amino acids?
A. Glutamic Acid
B. Glutamine
C. Glycine
D. Histidine
E. Isoleucine
Answer: A. Glutamic Acid (Glutamate) (Glu/E)
Carefully differentiate between Glutamic Acid structure and Aspartic Acid structure.
08. Following is the structure formula of one of the amino acids?
A. Glutamic Acid
B. Glutamine
C. Glycine
D. Histidine
E. Isoleucine
Answer: B. Glutamine (Gln/Q)
09. Following is the structure formula of one of the amino acids?
________H
A. Glutamic Acid
B. Glutamine
C. Glycine
D. Histidine
E. Isoleucine
Answer: C. Glycine (Gly/G)
10. Following is the structure formula of one of the amino acids?
A. Glutamic Acid
B. Glutamine
C. Glycine
D. Histidine
E. Isoleucine
Answer: D. Histidine (His/H)
11. Following is the structure formula of one of the amino acids?
A. Glutamic Acid
B. Glutamine
C. Glycine
D. Histidine
E. Isoleucine
Answer: E. Isoleucine (Ile/I)
12. Following is the structure formula of one of the amino acids?
A. Leucine
B. Lysine
C. Methionine
D. Phenylalanine
E. Proline
Answer: A. Leucine (Leu/L)
Carefully differentiate between Leucine and Isoleucine's structure.
13. Following is the structure formula of one of the amino acids?
A. Leucine
B. Lysine
C. Methionine
D. Phenylalanine
E. Proline
Answer: B. Lysine ( Lys/K)
14. Following is the structure formula of one of the amino acids?
A. Leucine
B. Lysine
C. Methionine
D. Phenylalanine
E. Proline
Answer: C. Methionine (Met/M)
15. Following is the structure formula of one of the amino acids?
A. Leucine
B. Lysine
C. Methionine
D. Phenylalanine
E. Proline
Answer: D. Phenylalanine (Phe/F)
16. Following is the structure formula of one of the amino acids?
A. Leucine
B. Lysine
C. Methionine
D. Phenylalanine
E. Proline
Answer: E. Proline (Pro/P)
17. Following is the structure formula of one of the amino acids?
A. Serine
B. Threonine
C. Tryptophan
D. Tyrosine
E. Valine
Answer: A. Serine (Ser/S)
18. Following is the structure formula of one of the amino acids?
A. Serine
B. Threonine
C. Tryptophan
D. Tyrosine
E. Valine
Answer: B. Threonine (Thr/T)
19. Following is the structure formula of one of the amino acids?
A. Serine
B. Threonine
C. Tryptophan
D. Tyrosine
E. Valine
Answer: C. Tryptophan (Trp/W)
20. Following is the structure formula of one of the amino acids?
A. Serine
B. Threonine
C. Tryptophan
D. Tyrosine
E. Valine
Answer: D. Tyrosine (Tyr/Y)
21. Following is the structure formula of one of the amino acids?
A. Serine
B. Threonine
C. Tryptophan
D. Tyrosine
E. Valine
Answer: E. Valine ( Val/V)
22. A linear sequence of Amino acids is following type of protein?
A. Primary structure
B. Secondary structure
C. Tertiary structure
D. Quaternary structure
Answer: A. Primary structure
Protein and enzymes structure has four main elements.
23. Two main structure of folded proteins of local amino acids that is Alpha helices and beta pleated sheets are type of protein?
A. Primary structure
B. Secondary structure
C. Tertiary structure
D. Quaternary structure
Answer: B. Secondary structure (occurs when the sequence of AA are linked by hydrogen bonds)
Two main structure: Alpha helices and formed from predominantly hydrophilic AA.
Beta-Pleated sheets: largely formed from hydrophobic AA. Both chains form large through hydrogen bonding.
24. A more complex folding and arrangements of these helices and sheets into a globular structure held togas through hydrogen bonds, ionic interaction and disulfide bonds?
A. Primary structure
B. Secondary structure
C. Tertiary structure
D. Quaternary structure
Answer: C. Tertiary structure
Tertiary amine also incorporate non amino acid component e. G metal ions structure elements.
25. A combination of two or more individual protein chains to form a multisubunit protein complex maintained by hydrogen bond, ionic and hydrophobic interactions?
A. Primary structure
B. Secondary structure
C. Tertiary structure
D. Quaternary structure
Answer: Quaternary structure (allows greater regulation of transport function such as hemoglobin and oxygen delivery and enzyme activity such as cooperatively and on off control.
26. An example of mutational change in DNA that can lead to abnormal protein such as a single nucleotide polymorphism (SNP) in the sequence of the coding DNA lead to alternate amino acid sequence?
A. Sickle cell anemia
B. Tuberculosis
C. Immunodeficiency
D. Autoimmune disease
Answer: A. Sickle cell anemia
Normal adults: hemoglobin has glutamic acid at the sixth position in the beta globin protein chain.
Because of a Single mutation A-T, sickle cell patient have a Valine at 6th position. This change in beta globin structure leads to change in overall hemoglobin structure.
Common Post translational modification of specific amino acids
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