PHARMACOLOGY QUIZZES 42 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is a neuromuscular blocker drug?
A. Atropine
B. Benztropine
C. Mecamylamine
D. Succinylcholine
E. Neostigmine

Answer: D. Succinylcholine

02. Which one of the following drugs belongs to an alkylating agent?
A. Gemcitabine
B. Melphalan
C. Lamivudine 
D. Fludarabine
E. Cladribine

Answer: B. Melphalan

03. Which of the following drug is a part of drugs for subcutaneous and systemic mycoses?
A. Ibandronate
B. Caspofungin
C. Ethambutol 
D. Furosemide 
E. A & B

Answer: B. Caspofungin


04. Ganglion blocker drug is following?
A. Atropine
B. Nicotine
C. Mecamylamine
D. Atracurium
E. B & C

Answer: B & C

05. Which one of the following drugs is a H² receptor Antagonist?
A. Omeprazole
B. Sucralfate
C. Cimetidine
D. Rabeprazole
 
Answer: C. Cimetidine

06. Which one of the following drugs belongs to drugs for hepatic viral infections?
A. Aluminium hydroxide 
B. Capreomycin
C. Entecavir 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: C. Entecavir

07. Which of the following drug is a part of drugs for subcutaneous and systemic mycoses?
A. Ibandronate
B. Anidulafungin
C. Ethambutol 
D. Furosemide 
E. A & B

Answer: B. Anidulafungin

08. Which one of the following drugs belongs to drugs for hepatic viral infections?
A. Aluminium hydroxide 
B. Capreomycin
C. Adefovir 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: C. Adefovir

09. Uric acid excretion is Increased by using one of the following options?
A. Probenecid
B. Sulfinpyrazone
C. Allopurinol
D.  A & B
E. All of the above

Answer: D. A & B

10. A drug that is used for Hypotrichosis of the eyelashes?
A. Carboprost
B. Dinoprostone
C. Epoprostenol
D. Treprostinil
E. Bimatoprost

Answer: E. Bimatoprost

11. Which of the following drug is a PGF2-Alpha analog?

A. Misoprostol

B. Dinoprostone

C. Epoprostenol

D. Treprostinil

E. Carboprost

Answer:  E. Carboprost

12. All of the following drugs have anti-inflammatory effects except?
A. Piroxicam
B. Mefenamic acid
C. Acetaminophen
D. Naproxen
E. ketorolac

Answer: C. Acetaminophen

13. Which of the following drugs are highly bound to albumin? 
A. Warfarin 
B. Digoxin   
C. Ibuprofen
D. A & B  
E. All of the above 

Answer: E. All of the above 


14. Which of the following drugs is used to inhibit viral neuraminidase?
A. Ibandronate
B. Zanamivir   
C. Capecitabine
D. Acyclovir 
E. Naftifine

Answer: B. Zanamivir 

15. What is the mechanism of action of zileuton?
A. Inhibition of calcium (Ca2+) channel activity
B. Inhibition of cytokine production
C. Inhibition of leukotriene production
D. Inhibition of mediator release
E. Inhibition of muscarinic receptor action

Answer: C. Inhibition of leukotriene production

16. Gynecomastia is the adverse effect of the following drug?
A. Flucytosine
B. Ketoconazole
C. Fluconazole
D. Griseofulvin


Answer: Ketoconazole
Because it inhibits the synthesis of human gonadal and adrenal steroids leading to decreased testosterone and cortisol production.

17. What is the antidote to snake bites?
A. Pralidoxime
B. Antivenin
C. Vitamin K 
D. Nalmefene 
E. A & B 

Answer: B. Antivenin

18. Which of the following side effect occurs in most of the patients when Alkylating agents and antimetabolites drugs are given in a therapeutically effective dose?
A. Gastrointestinal toxicity
B. Gonadal toxicity
C. Myelosuppression
D. Nausea
E. Thinning of hair


Answer: E. Thinning of hair

19. Which one of the following nicotinic antagonist drugs has the ability to lower blood pressure, a vasodilator?
A. Ipratropium
B. Trimethaphan
C. Tubocurarine
D. Succinylcholine

Answer: B. Trimethaphan

20. Which one of the following statements about the platelets is wrong?
A. Life of platelet 3-7 days 
B. TXA2 enhance aggregation 
C. PG2 decrease aggregation 
D. Platelet have nuclei 
E. Can't synthesize the new enzyme 

Answer: D. Platelet have nuclei 
Actually, platelets don't have nuclei so they can't synthesize new enzymes so the lack of thromboxane persists for the lifetime.

21. Amino acids contain following groups in their structural formula?

A. Amino group 

B. Carboxylic acid group 

C. Nitrogen Atom

D. A & B

E. All of these 

Answer: E. All of these (9 amino acids are essential in human nutrition His, Ile, Leu, Lys, Met, Phe, Thr, Trp and Val. They can't be synthesised from other AA.

Two groups: primary and secondary amines depending on their structure.

Primary amine: Nitrogen atom has only one bond to a carbon 

Atom

Secondary amine: Nitrogen atom is bonded to two carbon atoms 

22. Following Amino acids are conditionally essential in infants and young children but adults can produce from phenylalanine and methionine?

A. Tyrosine and Cysteine 

B. Lysine and Isoleucine 

C. Proline and Serine 

D. Theeonine and Valine 

Answer: A. Tyrosine and Cysteine 

23. Following 3 Amino acids are involved in critical metabolic pathways such as urea cycle (conversion of Ammonia to urea) to excrete nitrogen waste products?

A. Tyrosine, Lysine, Isoleucine 

B. Arginine, Ornithine, Citrulline

C. Cysteine, Valine, Threonine 

D. Valine, Serine, Proline 

Answer: B. Arginine, Ornithine, Citrulline

Urea cycle is the main pathway to excrete nitrogen waste product from protein metabolism. Urea cycle is coordinated in the cytoplasm and in the mitochondria of the cell.

24. Tripeptide glutathione is a first line cellular antioxidant formed from the following amino acids?

A. Tyrosine, Lysine, Isoleucine 

B. Arginine, Ornithine, Citrulline

C. Cysteine, Valine, Threonine 

D. Glutamine, cysteine, glycine 

Answer: D. Glutamine, cysteine, glycine 

Glutathione is synthesised in all tissues by a two step enzyme mediated process.